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Transcutaneous measurement and spectrum analysis of heart wall vibrations

机译：心脏壁振动的经皮测量和频谱分析

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摘要

For the noninvasive diagnosis of heart disease based on the acoustic and elastic characteristics of the heart muscle, it is necessary to transcutaneously measure small vibration signals, including components with an amplitude of less than 100 /spl mu/m, from various parts of the heart wall continuously for periods of more than several heartbeats in a wide frequency range up to 1 kHz. Such measurement, however, has not been realized by any ultrasonic diagnostic methods or systems to date. By introducing the constraint least-square approach, this paper proposes a new method for accurately tracking the movement of the heart wall based on both the phase and magnitude of the demodulated signal to determine the instantaneous position of the object so that the vibration velocity of the moving object can be accurately estimated. By this method, small vibrations of the heart wall with small amplitudes less than 100 /spl mu/m on the motion resulting from a heartbeat with large amplitude of 10 mm can be successfully detected with sufficient reproducibility in the frequency range up to several hundred Hertz continuously for periods of about 10 heartbeats. The resultant small vibration is analyzed not only in the time domain, but also in the frequency domain. As confirmed by the preliminary experiments herein reported, the new method offers potential for research in acoustical diagnosis of heart disease.
机译：对于基于心肌的声学和弹性特征的心脏病的非侵入性诊断，必须经皮测量来自心脏各个部位的小的振动信号，包括振幅小于100 / spl mu / m的分量在高达1 kHz的宽频率范围内连续不断地连续心跳多个心跳。然而，迄今为止，尚未通过任何超声诊断方法或系统实现这种测量。通过引入约束最小二乘方法，本文提出了一种新方法，该方法可基于解调信号的相位和幅度来精确跟踪心脏壁的运动，以确定物体的瞬时位置，从而使物体的振动速度降低。可以准确估计运动物体。通过这种方法，可以成功地检测到由振幅为10 mm的心跳引起的振幅小于100 / spl mu / m的振幅小的心壁振动，并且在高达几百赫兹的频率范围内具有足够的可重复性连续约10个心跳。由此产生的小振动不仅在时域中进行分析，而且还在频域中进行分析。如本文报道的初步实验所证实的那样，新方法为心脏病的声学诊断研究提供了潜力。

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