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Transcutaneous measurement and spectrum analysis of heart wallvibrations

机译:心脏壁振动的经皮测量和频谱分析

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For the noninvasive diagnosis of heart disease based on thenacoustic and elastic characteristics of the heart muscle, it isnnecessary to transcutaneously measure small vibration signals, includingncomponents with an amplitude of less than 100 Μm, from various partsnof the heart wall continuously for periods of more than severalnheartbeats in a wide frequency range up to 1 kHz. Such measurement,nhowever, has not been realized by any ultrasonic diagnostic methods ornsystems to date. By introducing the constraint least-square approach,nthis paper proposes a new method for accurately tracking the movement ofnthe heart wall based on both the phase and magnitude of the demodulatednsignal to determine the instantaneous position of the object so that thenvibration velocity of the moving object can be accurately estimated. Bynthis method, small vibrations of the heart wall with small amplitudesnless than 100 Μm on the motion resulting from a heartbeat with largenamplitude of 10 mm can be successfully detected with sufficientnreproducibility in the frequency range up to several hundred Hertzncontinuously for periods of about 10 heartbeats. The resultant smallnvibration is analyzed not only in the time domain, but also in thenfrequency domain. As confirmed by the preliminary experiments hereinnreported, the new method offers potential for research in acousticalndiagnosis of heart disease
机译:对于基于心肌的声学和弹性特征的无创性心脏病诊断,无需经皮测量来自心脏壁各个部位的小振动信号,包括振幅小于100微米的分量,连续持续多个心跳周期在高达1 kHz的宽频率范围内。但是,迄今为止,还没有任何超声诊断方法或系统实现这种测量。通过引入约束最小二乘方法,本文提出了一种新方法,该方法可以基于解调信号的相位和幅度来精确跟踪心壁的运动,从而确定物体的瞬时位置,从而可以使运动物体的振动速度准确估算。通过这种方法,可以成功地检测到由振幅为10 mm的大幅度心跳引起的幅度小于100μm的小幅度心壁小振动,并且在大约10个心跳的频率范围内连续地在高达数百赫兹的频率范围内具有足够的重现性。所得的小振动不仅在时域中进行分析,而且还在频域中进行分析。正如本文所报道的初步实验所证实的那样,该新方法为心脏病的声学诊断提供了研究潜力

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