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首页> 外文期刊>The American journal of hospice and palliative care >The use of transdermal fentanyl in pediatric oncology palliative care.
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The use of transdermal fentanyl in pediatric oncology palliative care.

机译：芬太尼透皮贴剂在儿科肿瘤姑息治疗中的应用。

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摘要

Transdermal fentanyl offers a noninvasive approach to the management of patients with opioid dependent and stable, chronic cancer pain. The transdermal delivery system offers distinct advantages where oral administration of opioids is difficult as a consequence of progressive disease and in patients whose compliance with oral medications is poor. Thirteen patients ranging in age from three years and nine months to 18 years and seven months were treated with transdermal fentanyl for between six hours and 112 days. All had previously been receiving oral morphine prior to the commencement of fentanyl and were transferred to fentanyl because of oral opioid side effects and poor oral compliance. Fentanyl was well tolerated and provided effective pain relief for 11 of 13 patients. Overall, patients and parents experienced satisfaction with fentanyl, both in terms of pain relief and improvement in quality of life.
机译：芬太尼透皮提供了一种无创方法来治疗阿片类药物依赖性和稳定的慢性癌症疼痛患者。透皮递送系统具有明显的优势，在这种情况下，由于进展性疾病而难以口服阿片类药物以及口服药物依从性差的患者。 13名年龄从3岁零9个月至18岁零7个月的患者接受了芬太尼透皮治疗6小时至112天。在口服芬太尼之前，所有患者以前都曾接受口服吗啡，由于口服阿片类药物的副作用和不良的口服依从性，因此全部转移至芬太尼。芬太尼耐受性良好，可为13例患者中的11例提供有效的疼痛缓解。总体而言，患者和父母在缓解疼痛和改善生活质量方面都对芬太尼感到满意。

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