Total syntheses of sterically locked phycocyanobilin derivatives bearing a 15Z-anti or a 15E-anti CD-ring component

Nishiyama K.; Kamiya A.; Hammam M.A.S.; Kinoshita H.; Fujinami S.; Ukaji Y.; Inomata K.

首页> 外文期刊>Bulletin of the Chemical Society of Japan >Total syntheses of sterically locked phycocyanobilin derivatives bearing a 15Z-anti or a 15E-anti CD-ring component

【24h】

Total syntheses of sterically locked phycocyanobilin derivatives bearing a 15Z-anti or a 15E-anti CD-ring component

机译：带有15Z-抗或15E-抗CD环成分的空间锁定藻蓝蛋白衍生物的总合成

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Total syntheses of sterically locked phycocyanobilin derivatives with a 15Z-anti or a 15E-anti CD-ring component were performed toward elucidation of the stereochemistry and function of the chromophore in phytochromes. In the course of the construction of a sterically locked 15E-anti CD-ring component employing 5-tosylpyrrolin-2-one derivatives as the D-ring, the Ts group was found to be rearranged under acidic conditions to give a mixture of regioisomers, both of which could be transformed into the same CD-ring precursor via detosylation with a base followed by Wittig-like coupling reaction. In addition, a sterically locked 15E-anti biliverdin derivative was also synthesized.

机译：为了阐明植物色素中的生色团的立体化学和功能，进行了具有15Z-抗或15E-抗CD-环组分的空间锁定的藻蓝蛋白衍生物的总合成。在使用5-甲苯磺酰基吡咯啉-2-一衍生物作为D环的立体锁定15E-抗CD环组件的构建过程中，发现Ts基团在酸性条件下发生了重排，从而形成了区域异构体的混合物，两者都可以通过与碱基解毒，然后进行类似Wittig的偶联反应，转化为相同的CD环前体。另外，还合成了空间锁定的15E-抗胆绿素衍生物。

著录项

来源
《Bulletin of the Chemical Society of Japan》 |2010年第11期|共14页
作者
Nishiyama K.; Kamiya A.; Hammam M.A.S.; Kinoshita H.; Fujinami S.; Ukaji Y.; Inomata K.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词

相似文献

外文文献
中文文献
专利

1. Total syntheses of sterically locked phycocyanobilin derivatives bearing a 15Z-anti or a 15E-anti CD-ring component [J] . Nishiyama K., Kamiya A., Hammam M.A.S., Bulletin of the Chemical Society of Japan . 2010,第11期

机译：带有15Z-抗或15E-抗CD环成分的空间锁定藻蓝蛋白衍生物的总合成
2. Synthesis of Sterically Fixed Phytochrome Chromophore Derivatives Bearing a 15E-Fixed or 15E-Anti-Fixed CD-Ring Component [J] . Soeta Takahiro, Ohashi Nobuhiko, Kobayashi Toshiharu, The Journal of Organic Chemistry . 2018,第18期

机译：具有15E固定或15E抗固定CD环组分的空间固定的植物色团衍生物的合成
3. Total Syntheses of Phycocyanobilin Derivatives Bearing a Modified A-Ring toward the Structure/Function Analysis of Phytochrome [J] . Daisuke Sawamoto, Hiroshi Nakamura, Hideki Kinoshita, Chemistry Letters . 2000,第12期

机译：带有修饰的A环的植物蓝藻素衍生物的总合成，对植物色素的结构/功能进行分析
4. Syntheses and Reduction of Cobalt Complexes Bearing a Sterically Demanding Phenanthroline-based Ligand [C] . Yohei Ueda, Hayato Tsurugi, Kazushi Mashima 日本化学会春季年会講演予稿集 . 2018

机译：含有空心苛刻的菲咯啉的配体的合成和还原钴复合物
5. Total Syntheses of Akuammiline Alkaloids and Nickel-Catalyzed Heck Cyclizations of Amide Derivatives. [D] . Moreno, Jesus. 2017

机译：Akuammiline生物碱的总合成和酰胺衍生物的镍催化的Heck环化。
6. Assembly of Synthetic Locked Phycocyanobilin Derivatives with Phytochrome in Vitro and in Vivo in Ceratodon purpureus and Arabidopsis [O] . Rui Yang, Kaori Nishiyama, Ayumi Kamiya, 2012

机译：紫藻和拟南芥体内和体内的植物色素合成的锁藻蓝藻素衍生物的组装
7. Total syntheses of sterically locked phycocyanobilin derivatives bearing a 15Z-anti or a 15E-anti CD-ring component [O] . Nishiyama, Kaori, Kamiya, Ayumi, Hammam, Mostafa A. S., 2010

机译：具有15Z-抗或15E-抗CD-环组分的空间锁定的藻蓝蛋白衍生物的总合成

Total syntheses of sterically locked phycocyanobilin derivatives bearing a 15Z-anti or a 15E-anti CD-ring component

摘要

著录项

相似文献

相关主题

期刊订阅