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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Signal transduction inhibitors, hibarimicins A, B, C, D and G produced by Microbispora - II. Structural studies
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Signal transduction inhibitors, hibarimicins A, B, C, D and G produced by Microbispora - II. Structural studies

机译:微双孢菌产生的信号转导抑制剂,hibarimicins A,B,C,D和G-II。结构研究

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摘要

The structure of hibarimicins A, B, C, D and G which are inhibitors for tyrosine specific protein kinase are determined using spectroscopic techniques. Hibarimicins described in this report consist of a common aglycon and six deoxyhexoses. The aglycon contains a highly oxidized naphtylnaphthoquinone as a chromophore. Among them, hibarimicin B was identical with angelmicin B. [References: 6]
机译:使用光谱技术确定酪氨酸特异性蛋白激酶抑制剂hibarimicins A,B,C,D和G的结构。本报告中描述的Hibarimicins由一个常见的糖苷配基和六个脱氧己糖组成。糖苷配基含有高度氧化的萘基萘醌作为生色团。其中,hibarimicin B与angelmicin B相同。[参考文献:6]

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