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首页> 外文期刊>The Journal of cardiovascular nursing >Cholesterol and Triglyceride Management 'If 1 Take My Medication, Can S Eat What I Want?'
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Cholesterol and Triglyceride Management 'If 1 Take My Medication, Can S Eat What I Want?'

机译：胆固醇和甘油三酸酯管理“如果我服药，我可以吃我想要的吗？”

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The medications we use for cholesterol and triglyceride lowering are powerful and have substantial outcome data. However, even with aggressive statin therapy, there is residual risk for recurrent cardiovascular events. Strict dietary modification has been shown to reduce low-density lipoprotem (LDL) cholesterol by 20% to 30%. Low-fat and Mediterranean-type diets have also been associated with atherosclerosis regression and fewer coronary heart disease events. On the other hand, a high-fat diet can produce postprandial lipemia and an increase in cardiovascular disease risk. Patients with atherogenic dyslipidemia (low high-density lipoprotem cholesterol, increased triglycerides and non-high-density lipoprotein cholesterol, small dense low-density lipoprotem particles) and visceral adiposity are particularly prone to postprandial lipemia. These individuals typically have insulin resistance, which is associated with endothelial dysfunction and an increased risk for thrombosis. Lifestyle intervention is the key to reducing postprandial lipemia, specifically weight reduction and increased physical activity. Although medications can improve postprandial lipemia, poor dietary choices can overwhelm the effects of medication and negatively impact the health of arteries, thus promoting atherosclerosis. Therefore, patients who are treated with medications for dyslipidemia must be counseled on consuming a heart-healthy diet.
机译：我们用于降低胆固醇和甘油三酸酯的药物功能强大，并具有大量的结果数据。但是，即使采用积极的他汀类药物疗法，也存在复发性心血管事件的残留风险。严格的饮食调节已显示可降低低密度脂蛋白（LDL）胆固醇20％至30％。低脂和地中海式饮食也与动脉粥样硬化消退和较少的冠心病事件相关。另一方面，高脂饮食会产生餐后血脂，增加心血管疾病的风险。动脉粥样硬化血脂异常（高密度脂蛋白胆固醇低，甘油三酯和非高密度脂蛋白胆固醇升高，低密度脂蛋白颗粒小）和内脏肥胖的患者特别容易发生餐后脂血症。这些个体通常具有胰岛素抵抗，这与内皮功能障碍和血栓形成的风险增加有关。生活方式干预是减少餐后血脂的关键，特别是减轻体重和增加体育锻炼。尽管药物可以改善餐后血脂，但不良的饮食选择可能使药物的作用不堪重负，并对动脉健康产生负面影响，从而促进动脉粥样硬化。因此，必须建议接受血脂异常药物治疗的患者食用有益心脏的饮食。

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