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Antiobesity effects of green tea catechins: a mechanistic review

机译:绿茶儿茶素的抗肥胖作用:机理综述

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Green tea catechins (GTC) are polyphenolic compounds present in the unfermented dried leaves of the plant, Camellia sinensis. Results from a number of randomized, controlled intervention trials have shown that consumption of GTC (270 mg to 1200 mg/day) may reduce body weight and fat. There are several proposed mechanisms whereby GTC may influence body weight and composition. The predominating hypothesis is that GTC influences sympathetic nervous system (SNS) activity, increasing energy expenditure and promoting the oxidation of fat. Caffeine, naturally present in green tea, also influences SNS activity, and may act synergistically with GTC to increase energy expenditure and fat oxidation. Other potential mechanisms include modifications in appetite, up-regulation of enzymes involved in hepatic fat oxidation, and decreased nutrient absorption. This article reviews the evidence for each of these purported mechanisms, with particular reference to studies in humans
机译:绿茶儿茶素(GTC)是植物茶树未发酵干叶中的多酚化合物。许多随机,对照干预试验的结果表明,服用GTC(270 mg至1200 mg /天)可以减轻体重和脂肪。有几种提议的机制可以影响GTC的体重和组成。最主要的假设是GTC影响交感神经系统(SNS)的活动,增加能量消耗并促进脂肪的氧化。天然存在于绿茶中的咖啡因也会影响SNS的活性,并可能与GTC协同作用以增加能量消耗和脂肪氧化。其他潜在的机制包括食欲改变,参与肝脂肪氧化的酶上调以及营养物质吸收减少。本文回顾了每种据称的机制的证据,特别是针对人类的研究

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