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首页> 外文期刊>The journal of sexual medicine >Sexual Functioning in Women with Mild and Severe Symptoms of Charcot-Marie-Tooth Disease
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Sexual Functioning in Women with Mild and Severe Symptoms of Charcot-Marie-Tooth Disease

机译：Charcot-Marie-Tooth病轻症和重症女性的性功能

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Introduction: Charcot-Marie-Tooth (CMT) disease is one of the most frequently inherited neurological disorders, and while it is known that individuals suffering from this condition have low quality of life, little is known about their sexual function and satisfaction. Aim: To describe the functioning on different domains of sexuality in a relatively large sample of women with CMT, provide comparisons between mildly and severely affected patients and between women with the two different types of CMT (demyelinating vs. axonal), and assess the relationship between sexual function and age of onset. Methods: Fifty-seven women (age: 18-60 years) were approached in a CMT rehabilitation clinic by a psychologist and administered the Italian version of the McCoy Female Sexuality Questionnaire (MFSQ). Data from 40 patients who had had sexual intercourse in the previous 4 weeks were analyzed. Main Outcome Measure: The main outcome measures are the factors MFSQ-SEX and MFSQ-PARTNER, which describe sexual functioning and sexual satisfaction with a partner, respectively. Results: Almost 30% of women did not engage in sexual intercourse with a partner. Overall sexual problems were more prominent in younger women and tended to be lower as age increased: this pattern was different from what was reported in previous studies in comparable samples of healthy Italian women. Severity of CMT was associated with better sexual functioning in the areas of desire, arousal, orgasm, and satisfaction, with women with more severe symptoms reporting greater functioning. Women with more severe CMT symptoms reported more pain during intercourse. Age of CMT onset and type of CMT (demyelinating vs. axonal) were not associated with differences in sexual functioning. Conclusions: Findings point to the importance of including assessment of sexual dysfunction in young women with mild CMT symptoms and the importance of providing sex therapy or counseling to these patients.
机译：简介：Charcot-Marie-Tooth（CMT）疾病是最常见的遗传性神经疾病之一，虽然已知患有这种疾病的人生活质量低下，但对其性功能和满意度知之甚少。目的：描述在相对大量的CMT妇女中性行为在不同领域的功能，比较轻度和重度患者之间以及两种不同CMT类型妇女（脱髓鞘与轴突）之间的关系，并评估其关系在性功能和发病年龄之间。方法：心理学家在CMT康复诊所接诊了57名妇女（年龄：18-60岁），并管理了意大利版的《麦考伊女性性行为问卷》（MFSQ）。分析了来自前4周发生过性行为的40名患者的数据。主要结局指标：主要结局指标是MFSQ-SEX和MFSQ-PARTNER因素，分别描述性功能和伴侣的性满意度。结果：几乎30％的女性未与伴侣进行性交。总体上，性问题在年轻女性中更为突出，并且随着年龄的增长而降低：这种模式与先前在健康意大利女性的可比较样本中的研究报告不同。 CMT的严重程度与在性欲，唤醒，性高潮和满足感方面的更好性功能有关，症状更严重的女性报告说其功能更强。患有严重CMT症状的女性在性交时报告更多疼痛。 CMT发作的年龄和CMT类型（脱髓鞘vs.轴突）与性功能的差异无关。结论：研究结果表明，包括对轻度CMT症状的年轻女性进行性功能障碍评估的重要性，以及为这些患者提供性治疗或咨询的重要性。

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