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The emperor of all maladies--the beginning of the beginning.

机译:所有疾病的皇帝-起点的开始。

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Richard Feynman, the eminent physicist, once said that "great ideas ... do not last unless they are passed purposely and clearly from generation to generation." In 1979, Horace Free-land Judson, in his magnificent The Eighth Day of Creation, passed to his generation the great ideas of molecular biology. Now, Sid-dhartha Mukherjee gives his generation an account of the great ideas of oncology in his Pulitzer Prize-winning book The Emperor of All Maladies: A Biography of Cancer (New York: Scribner, 2010). Muk-herjee's book unfolds the twists and turns, successes and failures, and hopes and despairs that led to our understanding of cancer's biology and its treatment, up to the point of the development of imatinib. It emphasizes oncology's development during the century between William Halsted's radical mastectomy and Brian Druk-er's imatinib. Mukherjee elucidates the extraordinarily complex story of the great surge in oncology that began in 1965.
机译:著名的物理学家理查德·费曼(Richard Feynman)曾说过:“伟大的想法……除非它们是有目的,明确地代代相传的,否则它们是不会持久的。” 1979年,霍勒斯·弗里兰德·贾德森(Horace Freeland Judson)在他的著作《第八天的创造》中将分子生物学的伟大思想传授给了他的世代。现在,西德达莎·穆克吉(Sid-dhartha Mukherjee)在他的普利策奖获奖著作《万恶之王:癌症传记》(纽约:斯克里布纳,2010年)中向他的世代介绍了肿瘤学的伟大思想。 Muk-herjee的书展现了曲折,成功与失败以及希望与绝望,这使我们对癌症的生物学及其治疗方法有了更深入的了解,直至伊马替尼的发展。它强调了威廉·哈尔斯泰德(William Halsted)的根治性乳房切除术和布莱恩·德鲁克(Brian Druk-er)的伊马替尼之间的世纪肿瘤学发展。穆克吉(Mukherjee)阐述了始于1965年的肿瘤学激增的异常复杂故事。

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