Beraprost Sodium, an Orally Active Prostaglandin I_2 Analog, Improves Renal Anemia in Hemodialysis Patients With Peripheral Arterial Disease

Hidekazu Moriya; Kunihiro Ishioka; Kenjiro Honda; Machiko Oka; Kyoko Maesato

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Beraprost Sodium, an Orally Active Prostaglandin I_2 Analog, Improves Renal Anemia in Hemodialysis Patients With Peripheral Arterial Disease

机译：贝拉前列素钠，一种口服活性前列腺素I_2类似物，可改善患有外周动脉疾病的血液透析患者的肾性贫血

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Beraprost sodium (BPS) is a stable, orally active prostaglandin I_2 (PGI2) analog with antiplatelet and vasodilating properties. It has been reported that PGI2 has pleiotropic effects that are anti-inflammatory and anti-atherogenic. In this study, we aim to determine the relationship between PGI_2 and renal anemia. We conducted a prospective randomized trial including 20 hemodialysis patients. Ten patients were assigned to be treated with 120 mug/day of BPS and the other patients were assigned to a control group.

机译：贝拉前列素钠（BPS）是一种稳定的口服活性前列腺素I_2（PGI2）类似物，具有抗血小板和血管舒张特性。据报道，PGI2具有抗炎和抗动脉粥样硬化的多效作用。在这项研究中，我们旨在确定PGI_2与肾性贫血之间的关系。我们进行了一项前瞻性随机试验，包括20名血液透析患者。十名患者被分配接受每天120杯的BPS治疗，其他患者被分配为对照组。

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《Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy》 |2010年第5期|共5页
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Hidekazu Moriya; Kunihiro Ishioka; Kenjiro Honda; Machiko Oka; Kyoko Maesato;
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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
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1. Beraprost Sodium, an Orally Active Prostaglandin I_2 Analog, Improves Renal Anemia in Hemodialysis Patients With Peripheral Arterial Disease [J] . Hidekazu Moriya, Kunihiro Ishioka, Kenjiro Honda, Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy . 2010,第5期

机译：贝拉前列素钠，一种口服活性前列腺素I_2类似物，可改善患有外周动脉疾病的血液透析患者的肾性贫血
2. The efficacy of Oral Beraprost Sodium, a prostaglandin I_2 analogue, for treating intermittent claudication in patients with arteriosclerosis obliterans [J] . T. MATSUMOTO, K. IWASA, R. KYURAGI, International angiology: A journal of the International Union of Angiology . 2010,第Suppla1期

机译：前列腺素I_2类似物口服贝拉前列素钠治疗闭塞性动脉硬化患者的间歇性lau行
3. Randomized pilot trial between prostaglandin I2 analog and anti-platelet drugs on peripheral arterial disease in hemodialysis patients [J] . OhtakeT., SatoM., NakazawaR., Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy . 2014,第1期

机译：前列腺素I2类似物与抗血小板药物在血液透析患者外周动脉疾病之间的随机先导试验
4. Modified LDL Decreases the Binding of Prostaglandin E_2,I_2 and E_1 onto Monocytes in Patients with Peripheral Vascular Disease [C] . S.R. Li, Q. Yang, E. Koller, NATO Advanced Study Institute on Vascular Endothelium : Mechanisms of Cell Signaling . 1999

机译：改性LDL将前列腺素E_2，I_2和E_1的结合降低到外周血血管疾病患者的单核细胞上
5. Evaluating physiological measures and anemia management in pediatric patients with end stage renal disease: Peritoneal versus hemodialysis. [D] . Njuguna, Gladys Wacheke. 2016

机译：评估终末期肾脏疾病的小儿患者的生理指标和贫血管理：腹膜透析与血液透析。
6. Effects of Beraprost Sodium on Subjective Symptoms in Diabetic Patients with Peripheral Arterial Disease [O] . Hang Seob Yoon, Woo Jin Choi, Il Hoon Sung, 2013

机译：贝拉前列素钠对糖尿病患者外周动脉疾病主观症状的影响
7. Randomized Pilot Trial Between Prostaglandin I2Analog and Anti-Platelet Drugs on Peripheral Arterial Disease in Hemodialysis Patients [O] . Takayasu Ohtake, Motoyoshi Sato, Ryoichi Nakazawa, 2013

机译：血液透析患者外周动脉疾病前列腺素I2ANALOG与抗血小板药物的随机试验试验

Beraprost Sodium, an Orally Active Prostaglandin I_2 Analog, Improves Renal Anemia in Hemodialysis Patients With Peripheral Arterial Disease

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