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Effect of copper edetate injection in dry pregnant cows on hematology, blood metabolites, weight gain and health of calves

机译:干燥怀孕母牛注射乙二胺四乙酸铜对血液学,血液代谢物,体重增加和犊牛健康的影响

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The objectives of the present study was to investigate the effects of the copper injection and injection timing to pregnant dairy cows at dry period on the hematology, some serum metabolites, health and growth of their calves. Thirty Holstein cows at the dry period were assigned to the three following experimental groups: 1) control (injections of 2.5 ml normal saline), 2) test 1 (125 mg Cu as copper edetate injection at the first week of the dry period) and 3) test 2 (125 mg Cu as copper edetate injection at the third week of the dry period). Ten milliliters of jugular blood was taken from all calves 24-48 h after birth and at 7, 14, 21 and 28 days of age for measuring hematological and biochemical parameters. For evaluation of growth and health, body weight of all of the calves was measured at birth and at the end of the trial, and the health of calves was checked by a technician twice a day and any sign of illness, treatment (if needed) and duration of illness was recorded. Copper treatment was proved to have a significant effect on the counts of WBC (lower in test 2, higher in test 1), lymphocyte (lower in test 2, higher in test 1) and the concentrations of fibrinogen (lower in test 1, higher in test 2), cholesterol (lower in control, higher in test 1) and copper (lower in test 1, higher in test 2) ( < 0.05). Age (sampling time) also influenced most measured parameters ( < 0.05) except values of WBC, neutrophil, monocyte, globulin and concentrations of iron, zinc and copper.
机译:本研究的目的是研究铜注射和注射时间对干燥期怀孕的奶牛的血液学,某些血清代谢物,健康状况以及小牛生长的影响。将干燥期的30头荷斯坦奶牛分为以下三个实验组:1)对照(注射2.5 ml生理盐水),2)试验1(在干燥期的第一周注射125 mg铜作为乙二胺四乙酸铜)和3)测试2(在干燥期的第三周注射125 mg铜作为乙二胺四乙酸铜)。出生后24、48h,7、14、21和28日龄时从所有小牛取10毫升颈静脉血,以测量血液学和生化指标。为了评估生长和健康状况,在出生时和试验结束时测量了所有小牛的体重,并由技术人员每天两次检查小牛的健康,并检查是否有任何疾病迹象,治疗(如果需要)并记录病程。事实证明,铜处理对WBC的计数(测试2较低,测试1较高),淋巴细胞(测试2较低,测试1较高)和纤维蛋白原浓度(测试1较低,较高)具有显着影响。在测试2中),胆固醇(在对照组中较低,在测试1中较高)和铜(在测试1中较低,在测试2中较高)(<0.05)。年龄(采样时间)也影响大多数测得的参数(<0.05),除了白细胞,中性粒细胞,单核细胞,球蛋白的浓度以及铁,锌和铜的浓度。

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