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The IMGT/HLA and IPD databases.

机译:IMGT / HLA和IPD数据库。

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摘要

The IMGT/HLA database (www.ebi.ac.uk/imgt/hla) has provided a centralized repository for the sequences of the alleles named by the WHO Nomenclature Committee for Factors of the HLA System since 1998. Since its initial release, the database has rapidly grown in size and is recognized as the primary source of information for the study of sequences of the human major histocompatibility complex. The Immuno Polymorphism Database (IPD; www.ebi.ac.uk/ipd) is a set of specialist databases related to the study of polymorphic genes in the immune system. The IPD currently consists of four databases: IPD-KIR contains the allelic sequences of killer-cell immunoglobulin-like receptors; IPD-MHC is a database of sequences of the major histocompatibility complex of different species; IPD-HPA contains alloantigens expressed only on platelets (human platelet antigens or HPA); and IPD-ESTDAB provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologically characterized melanoma cell lines.
机译:IMGT / HLA数据库(www.ebi.ac.uk/imgt/hla)自1998年以来就为世界卫生组织HLA系统因子命名委员会命名的等位基因序列提供了一个集中式存储库。数据库的规模迅速增长,被认为是人类主要组织相容性复合体序列研究的主要信息来源。免疫多态性数据库(IPD; www.ebi.ac.uk/ipd)是一组与免疫系统中多态性基因研究有关的专业数据库。 IPD目前由四个数据库组成:IPD-KIR包含杀伤细胞免疫球蛋白样受体的等位基因序列; IPD-MHC是不同物种主要组织相容性复合体序列的数据库; IPD-HPA包含仅在血小板上表达的同种抗原(人血小板抗原或HPA); IPD-ESTDAB提供对欧洲可搜索肿瘤细胞系数据库的访问,该数据库是具有免疫学特征的黑色素瘤细胞系的细胞库。

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