Heterogeneously catalyzed diastereoselective synthesis of 2-nitro-1,3-di(pyridin-2-yl)propane-1,3-diols

Schulza M.; Wimmerb K.; Gorlsb H.; Westerhausen M.

首页> 外文期刊>Zeitschrift fur Naturforschung, B. A Journal of Chemical Sciences >Heterogeneously catalyzed diastereoselective synthesis of 2-nitro-1,3-di(pyridin-2-yl)propane-1,3-diols

【24h】

Heterogeneously catalyzed diastereoselective synthesis of 2-nitro-1,3-di(pyridin-2-yl)propane-1,3-diols

机译：2-硝基-1,3-二吡啶（吡啶-2-基）丙烷-1,3-二醇的非均相催化非对映选择性合成

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

2-Nitro-1,3-di(pyridin-2-yl)propane-1,3-diols 4a, 4b are prepared via nitroaldol (Henry) reaction in two separate steps by straightforward procedures. The employment of two solids as catalysts, namely the hydrotalcite Syntal 696? and the ion exchange resin Amberlyst A21? allows a simple work-up and leads to the diastereoselective formation of the (R,R)- and (S,S)-isomers. The solid-state structures of 4a, 4b as well as of their precursor compounds 3a and 3b were determined. Reaction of 4a with zinc chloride yields a mononuclear zinc chloride complex. To circumvent retro-reactions, trialkylsilyl protective groups are deployed.

机译：2-硝基-1,3-二（吡啶-2-基）丙烷-1,3-二醇4a，4b是通过硝基醛（Henry）反应在两个单独的步骤中通过简单的方法制备的。使用两种固体作为催化剂，即水滑石Syntal 696？和离子交换树脂Amberlyst A21？允许简单的后处理并导致（R，R）-和（S，S）异构体的非对映选择性形成。确定了4a，4b及其前体化合物3a和3b的固态结构。 4a与氯化锌反应生成单核氯化锌配合物。为了规避逆反应，部署了三烷基甲硅烷基保护基。

著录项

来源
《Zeitschrift fur Naturforschung, B. A Journal of Chemical Sciences》 |2011年第6期|共13页
作者
Schulza M.; Wimmerb K.; Gorlsb H.; Westerhausen M.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词
Configuration Determination; Heterogeneous Catalysis; N; O Ligands; Nitroaldol Reaction; Solid-state Structures;

机译：构型确定;均相催化;N;O配体;硝基醛醇缩合反应;固态结构;

相似文献

外文文献
中文文献
专利

1. Heterogeneously catalyzed diastereoselective synthesis of 2-nitro-1,3-di(pyridin-2-yl)propane-1,3-diols [J] . Schulza M., Wimmerb K., Gorlsb H., Zeitschrift fur Naturforschung, B. A Journal of Chemical Sciences . 2011,第6期

机译：2-硝基-1,3-二吡啶（吡啶-2-基）丙烷-1,3-二醇的非均相催化非对映选择性合成
2. Synthesis, structure, and luminescent properties of two novelpolynuclear complexes of 1,3-di(pyridin-2-yl)propane-1,3-dione [J] . J-in-Ting Tan, Wen-Jie Zhao, San-Ping Chen, Chemicke Zvesti . 2012,第1期

机译：1,3-二（吡啶-2-基）丙烷-1,3-二酮的两种新型多核配合物的合成，结构和发光性质
3. Synthesis of Quinolines by Iron-Catalyzed Reaction of Anilines with Propane-1,3-diol [J] . Khusnutdinov R. I., Bayguzina A. R., Aminov R. I. Russian Journal of General Chemistry . 2015,第12期

机译：铁催化苯胺与丙烷1,3-二醇的合成喹啉
4. Oxidative cleavage of 1,3-diols catalyzed by silver acetylide [C] . ISHIKAWA Shingo, FUGAMI Keigo 日本化学会春季年会講演予稿集 . 2018

机译：乙酰乙酰氨基催化的1,3-二醇的氧化切割
5. Diastereoselective Synthesis of Seven-Membered Ring trans-Alkenes and Development of Stereospecific Nickel-Catalyzed Cross-Coupling Reactions. [D] . Greene, Margaret A. 2013

机译：七元环反式烯烃的非对映选择性合成和立体特异性镍催化的交叉偶联反应的发展。
6. [2,6-Bis(biphenyl-4-yl)-4-hydroxy-4-(pyridin-2-yl)cyclohexane-1,3-diyl]bis[(pyridin-2-yl)methanone]–butan-2-one (1/1) [O] . Hoong-Kun Fun, Chin Wei Ooi, S. Samshuddin, 2015

机译：[2,6-双（联苯-4-基）-4-羟基-4-（吡啶-2-基）环己烷-1,3-二基]双[（吡啶-2-基）甲酮] –丁烷-2 -一（1/1）
7. Highly Diastereoselective Heterogeneously-Catalyzed Hydrogenation of Enamines for the Synthesis of Chiral beta-Amino Acid Derivatives [O] . -1

机译：高度自映选择性的非均匀催化烯胺的氢化，用于合成手性β-氨基酸衍生物

Heterogeneously catalyzed diastereoselective synthesis of 2-nitro-1,3-di(pyridin-2-yl)propane-1,3-diols

摘要

著录项

相似文献

相关主题

期刊订阅