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首页> 外文期刊>Circulation journal >Re: Effect of carvedilol on plasma adiponectin concentration in patients with chronic heart failure.
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Re: Effect of carvedilol on plasma adiponectin concentration in patients with chronic heart failure.

机译：回复：卡维地洛对慢性心力衰竭患者血浆脂联素浓度的影响。

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To the Editor:We read with great interest the study by Yamaji et al,which concluded that carvedilol decreases plasma adiponectin concentration and that the decrease is associated with the improvement of left ventricular ejection fraction after treatment with carvedilol in patients with chronic heart failure. The methods and interpretation of the results, however, raise several concerns.The serum concentration of adiponectin was significantly increased in patients with chronic heart failure, which was a significant predictor of a worse prognosis in patients with chronic heart failure.2However, the serum concentration of adiponectin in patients with ischemic cardiomyopathy is lower than that in patients with other forms of chronic heart failure.
机译：致编者：我们非常感兴趣地阅读了Yamaji等人的研究，该研究得出的结论是卡维地洛降低血浆脂联素浓度，且降低与慢性心力衰竭患者接受卡维地洛治疗后左心室射血分数的改善有关。然而，结果的方法和解释引起了一些关注：慢性心力衰竭患者的血清脂联素浓度显着升高，这是慢性心力衰竭患者预后较差的重要预测指标2。缺血性心肌病患者的脂联素水平低于其他形式的慢性心力衰竭患者。

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