...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>JAMA otolaryngology-- head & neck surgery >Increased Risk of Sudden Sensorineural Hearing Loss in Patients With Human Immunodeficiency Virus Aged 18 to 35 Years A Population-Based Cohort Study
【24h】

Increased Risk of Sudden Sensorineural Hearing Loss in Patients With Human Immunodeficiency Virus Aged 18 to 35 Years A Population-Based Cohort Study

机译：一项基于人群的队列研究显示，年龄在18至35岁之间的人类免疫缺陷病毒患者突然感觉神经性听力丧失的风险增加

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Importance: No case series or cohort studies to date in the English literature have evaluated sudden sensorineural hearing loss (SSHL) in patients with human immunodeficiency virus (HIV). Objective: To investigate the risk of developing SSHL in patients with HIV. Design and Setting: Retrospective cohort population-based study using data from the Taiwan National Health Insurance Research Database. Participants: In total, 8760 patients with HIV and 43 800 control subjects without HIV were selected from insurance claims between January 1, 2001, and December 31, 2006. Main Outcome Measure: The incidence of SSHL was assessed and determined at the end of 2009. Results: Among patients aged 18 to 35 years, the incidence of SSHL was 2.17-fold higher in the HIV group than in the control group (4.32 vs 1.99 per 10 000 person-years, P=.03). The risk of developing SSHL increased with HIV infection; an adjusted hazard ratio of 2.169 (95% CI, 1.071-4.391) was calculated using a Cox proportional hazards regression model. Among male patients, the incidence of developing SSHL was 2.23-fold higher (95% CI, 1.06-4.69) in the HIV group than in the control group. The incidence of SSHL did not differ significantly between the HIV group and the control group for patients 36 years or older. Conclusion and Relevance: Human immunodeficiency virus infection is significantly associated with an increased risk of developing SSHL in patients aged 18 to 35 years, particularly among male patients.
机译：重要性：迄今为止，英语文献中尚无病例系列或队列研究评估人免疫缺陷病毒（HIV）患者的突然感觉神经性听力丧失（SSHL）。目的：探讨艾滋病毒患者发展SSHL的风险。设计与设置：使用台湾国家健康保险研究数据库中的数据进行的回顾性队列研究。参与者：在2001年1月1日至2006年12月31日期间，共从保险索赔中选择了8760例HIV感染者和43 800例无HIV的对照对象。主要结果指标：在2009年底评估并确定SSHL的发生结果：在18至35岁的患者中，HIV组SSHL的发生率比对照组高2.17倍（每2万人年4.32比1.99，P = .03）。 HIV感染会导致发展SSHL的风险增加;使用Cox比例风险回归模型计算出的调整后风险比为2.169（95％CI，1.071-4.391）。在男性患者中，HIV组患SSHL的发生率比对照组高2.23倍（95％CI，1.06-4.69）。对于36岁或以上的患者，HIV组与对照组之间SSHL的发生率没有显着差异。结论与相关性：在18至35岁的患者中，特别是在男性患者中，人类免疫缺陷病毒感染与SSHL风险增加显着相关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号