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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Effect of triazine derivative added to denture materials on a microcosm biofilm model.
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Effect of triazine derivative added to denture materials on a microcosm biofilm model.

机译:将三嗪衍生物添加到义齿材料上对微观生物膜模型的影响。

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摘要

The aim of this study was to assess the effect of triazine incorporation to denture materials on biofilm formation of saliva derived from microcosms of patients who are positive for Candida albicans. Biofilms were formed on microwave-cured acrylic resin, one hard denture liner, and two soft denture liners containing 0, 2.5, 5, and 10% triazine. For experimental subset (n = 10), mechanical properties of the materials and colony-forming unit counts from the biofilms formed on the materials were assessed. Flexural strength and modulus decreased with the addition of 2.5% triazine (p < 0.01). In general, the addition of 5 and 10% triazine leaded to more soluble materials (p < 0.001). Saliva donor with candidiasis resulted in higher counts of total microorganisms (p = 0.0294) and Streptococci (p = 0.0008). Soft denture liners showed the highest counts for total microorganisms, Streptococci, and Candida species (p < 0.001). The addition of triazine directly to denture materials was not beneficial in reducing biofilm formation in a complex biofilm model.
机译:这项研究的目的是评估将三嗪掺入义齿材料中对白色念珠菌阳性患者的缩微来源唾液生物膜形成的影响。生物膜在微波固化的丙烯酸树脂,一个硬义齿衬垫和两个包含0、2.5、5和10%三嗪的软义齿衬垫上形成。对于实验子集(n = 10),评估了材料的机械性能和在材料上形成的生物膜的菌落形成单位数。加入2.5%三嗪会降低抗弯强度和模量(p <0.01)。通常,添加5%和10%的三嗪会产生更多可溶物质(p <0.001)。念珠菌病的唾液供体导致总微生物(p = 0.0294)和链球菌(p = 0.0008)的计数更高。软义齿衬里显示出总微生物,链球菌和念珠菌种类的最高数量(p <0.001)。在复杂的生物膜模型中,将三嗪直接添加到义齿材料中不利于减少生物膜的形成。

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