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首页> 外文期刊>Journal of cutaneous pathology >Could follicular helper T-cells play a role in primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphomas?
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Could follicular helper T-cells play a role in primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphomas?

机译:滤泡性辅助性T细胞是否可以在原发性皮肤CD4 +中小型多形性T细胞淋巴瘤中发挥作用?

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摘要

Primary cutaneous small/medium-sized pleomorphic CD4+ T-cell lymphoma (PCSMTCL) represents about 3% of all primary cutaneous T-cell lymphomas. It is a provisional entity in the new WHO-EORTG classification. PCSMTCL usually presents as a solitary plaque or tumor on the head, neck or extremities. Most patients have a relatively indolent course with a 5-year survival of 60-80%. A recent report in the literature suggests that prognosis may be dependent on the size of the lesions, proliferative index, and the number of infiltrating GD8+ T cells.
机译:原发性皮肤中小型多形性CD4 + T细胞淋巴瘤(PCSMTCL)约占所有原发性皮肤T细胞淋巴瘤的3%。它是新的WHO-EORTG分类中的临时实体。 PCSMTCL通常表现为头部,颈部或四肢上的孤立斑块或肿瘤。大多数患者的病程相对缓慢,5年生存率为60-80%。文献中的最新报告表明,预后可能取决于病变的大小,增殖指数以及浸润的GD8 + T细胞的数量。

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