...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of endovascular therapy: an official journal of the International Society of Endovascular Specialists >Wall mechanics of the stented rabbit aorta: long-term study and correlation with histological findings.
【24h】

Wall mechanics of the stented rabbit aorta: long-term study and correlation with histological findings.

机译：支架兔主动脉壁力学：长期研究及其与组织学发现的关系。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: To evaluate long-term changes in arterial wall mechanics induced by stenting of the rabbit aorta. METHODS: Eighteen New Zealand white rabbits had initial stent deployment (3x8 mm Multilink) at 110% of the pre-stenting abdominal aortic diameter. Group A (n=10) had no postdeployment stent expansion and group B (n=8) had 30% overdilation of the stent. A noninvasive B-mode ultrasound examination coupled with image processing allowed measurement of diameters at systole and diastole and the calculation of diameter compliance. Measurements were performed before stenting and compared to those recorded immediately after stenting and at 3 months at 3 locations: upstream from the stent, at the stent level, and downstream from the stent. Measurements were also compared among measurement sites. The pathological study included measurement of intimal thickening and calculation of an injury score. RESULTS: At the stent level, diameter compliance was significantly lower after initial stenting and at 3 months than before stenting (group A: p<0.005; group B: p<0.001) and than downstream or upstream from the stent (group A: p<0.0001, group B: p<0.005). No significant difference in diameter compliance was found between groups A and B. In group B, intimal thickening and the injury score were greater than in group A (p<0.05 and p<0.0001, respectively). CONCLUSIONS: Endovascular stenting of the rabbit aorta impairs wall mechanics. Performing 30% overdilation of the stent does not worsen this impairment but induces greater in-stent intimal hyperplasia.
机译：目的：评估由兔主动脉支架置入引起的动脉壁力学的长期变化。方法：18只新西兰白兔在支架前腹主动脉直径的110％处初始支架展开（3x8 mm Multilink）。 A组（n = 10）没有部署后支架扩张，B组（n = 8）支架过度扩张30％。结合图像处理的无创B型超声检查可以测量收缩期和舒张期的直径并计算直径顺应性。在支架置入前进行测量，并将其与支架置入后立即进行的测量以及三个月后三个位置的测量值进行比较：三个位置：支架上游，支架水平和支架下游。还对测量地点之间的测量结果进行了比较。病理研究包括内膜增厚的测量和损伤评分的计算。结果：在支架水平上，初始支架置入后和3个月时的直径顺应性明显低于支架置入前（A组：p <0.005; B组：p <0.001），且低于支架下游或上游（A组：p <0.0001，B组：p <0.005）。 A组和B组之间的直径顺应性没有显着差异。B组的内膜增厚和损伤评分均高于A组（分别为p <0.05和p <0.0001）。结论：兔主动脉的血管内支架术损害了壁力学。对支架进行30％的过度扩张不会加剧这种损害，但会引起更大的支架内膜内膜增生。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号