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首页> 外文期刊>Journal of glaucoma >Ocular hypertension and diabetes mellitus in the Beijing Eye Study.
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Ocular hypertension and diabetes mellitus in the Beijing Eye Study.

机译：在北京眼科研究中的高眼压和糖尿病。

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摘要

PURPOSE: To determine prevalence and associated factors of ocular hypertension in the adult Chinese population. METHODS: The Beijing Eye Study, a population-based prevalence study, included 4439 subjects out of 5324 subjects with an age of 40+ years invited to participate (response rate 83.4%). From the 4439 individuals, 4224 (95.2%) subjects fulfilled the inclusion criteria of the present study, that is, available readable optic disc photographs, a nonglaucomatous appearance of the optic disc, and a normal visual field in the case of an intraocular pressure higher than 21 mm Hg. The participants underwent an interview, a detailed ophthalmic examination, blood pressure measurements, and examination of blood samples. Ocular hypertension was defined as an intraocular pressure higher than 21 mm Hg with a normal appearance of the optic nerve head and no defects in frequency doubling perimetry. RESULTS: Ocular hypertension was detected in 299 (3.6%) eyes (prevalence rate: 3.63%+/-0.21%) of 160 (3.8%) subjects (prevalence rate: 3.79%+/-0.29%). In multiple regression analysis, ocular hypertension was significantly associated with serum levels of cholesterol [P=0.006; odds ratio (OR): 1.34; 95% confidence interval (CI): 1.09-1.64], presence of diabetes mellitus (P=0.03; OR: 1.45; 95% CI: 1.04-2.07) and arterial hypertension (P<0.001; OR: 3.18; 95% CI: 1.86-5.43). Ocular hypertension was not significantly associated with age, sex, urban or rural region, refractive error, anterior chamber depth, optic disc area, and area of beta zone of parapapillary atrophy. CONCLUSIONS: Ocular hypertension has a frequency of about 3.6% in the adult Chinese population with an age of 40+ years. Associated factors are diabetes mellitus, arterial hypertension, and elevated serum cholesterol levels. Diabetes mellitus, arterial hypertension, and elevated serum cholesterol concentrations should be checked in ocular hypertensive subjects.
机译：目的：确定中国成年人口高眼压的患病率及其相关因素。方法：以人群为基础的患病率研究“北京眼研究”包括5324名年龄在40岁以上的受试者中的4439名受试者（应答率为83.4％）。在4439位个体中，有4224位（95.2％）的受试者符合本研究的纳入标准，即可获得的可读视盘照片，视盘的非青光眼外观以及在眼压高的情况下的正常视野超过21毫米汞柱。参加者进行了访谈，详细的眼科检查，血压测量以及血液样本检查。高眼压定义为眼压高于21 mm Hg，视神经头正常，倍频视野检查无缺陷。结果：在160名（3.8％）受试者（患病率：3.79％+ /-0.29％）中，有299眼（3.6％）检出了高眼压（患病率：3.63％+ /-0.21％）。在多元回归分析中，高眼压与血清胆固醇水平显着相关[P = 0.006;比值比（OR）：1.34; 95％置信区间（CI）：1.09-1.64]，存在糖尿病（P = 0.03; OR：1.45; 95％CI：1.04-2.07）和动脉高压（P <0.001; OR：3.18; 95％CI： 1.86-5.43）。高眼压与年龄，性别，城市或农村地区，屈光不正，前房深度，视盘面积以及乳头旁萎缩的β区面积无显着相关性。结论：40岁以上的中国成年人口中，高眼压症的发病率约为3.6％。相关因素是糖尿病，动脉高血压和血清胆固醇水平升高。眼高血压患者应检查糖尿病，动脉高血压和血清胆固醇浓度升高。

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