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首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >The spectrum of autoimmune encephalopathies
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The spectrum of autoimmune encephalopathies

机译：自身免疫性脑病的光谱

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Despite being a potentially reversible neurological condition, no clear guidelines for diagnosis or management of autoimmune encephalitis exist. In this study we analyzed clinical presentation, laboratory and imaging characteristics, and outcome of autoimmune encephalitis from three teaching hospitals. Non-paraneoplastic autoimmune encephalitis associated with antibodies against membrane antigens was the most common syndrome, especially in the pediatric population. Clinical outcome was better for patients with shorter latency from symptom onset to diagnosis and initiation of immunomodulation. Patients with underlying malignancy were less likely to respond well to immunomodulatory therapy. The clinical spectrum of autoimmune encephalitis is fairly broad, but prompt recognition and treatment often leads to excellent outcome. (C) 2015 Elsevier B.V. All rights reserved.
机译：尽管是潜在的可逆神经系统疾病，但尚无明确的指南来诊断或管理自身免疫性脑炎。在这项研究中，我们分析了三所教学医院的临床表现，实验室和影像学特征以及自身免疫性脑炎的结局。与膜抗原抗体相关的非副肿瘤性自身免疫性脑炎是最常见的综合征，尤其是在儿科人群中。对于从症状发作到诊断和免疫调节开始的潜伏期较短的患者，临床结果更好。潜在恶性肿瘤患者对免疫调节疗法的反应不太可能。自身免疫性脑炎的临床范围相当广泛，但是迅速的识别和治疗通常会导致出色的结果。 （C）2015 Elsevier B.V.保留所有权利。

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