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首页> 外文期刊>Journal of paediatrics and child health >Snoring is not associated with adverse effects on blood pressure, arterial structure or function in 8-year-old children: the Childhood Asthma Prevention Study (CAPS).
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Snoring is not associated with adverse effects on blood pressure, arterial structure or function in 8-year-old children: the Childhood Asthma Prevention Study (CAPS).

机译：打8-与8岁儿童的血压，动脉结构或功能的不良影响无关：儿童哮喘预防研究（CAPS）。

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AIMS: To study the association between childhood snoring and cardiovascular risk factors. METHODS: Cross-sectional analyses of a population-based birth cohort, who had been participants in a randomised controlled trial of interventions to prevent asthma and who were assessed at age 8 years. The presence and frequency of snoring were assessed by parent-completed questionnaire. We measured a wide range of cardiovascular function markers including non-fasting serum lipoproteins, blood pressure, high-sensitivity C-reactive protein, carotid artery intima media thickness (by ultrasound), brachial pulse wave velocity and augmentation index (by applanation tonometry). RESULTS: Of 409 children whose snoring status was assessed at age 8 years, 321 had lipid and 386 had arterial structure and function measurements. Snoring was not independently associated with blood pressure, carotid artery intima media thickness or measures of arterial stiffness (all P > 0.05). Increasing snoring frequency was independently associated with lower high-density lipoprotein cholesterol (-0.032 g/dL per step, 95% confidence interval -0.060 to -0.003), although the difference in high-density lipoprotein between snorers and non-snorers was not significant (P = 0.052). An association of snoring frequency with brachial pulse wave velocity differed according to body mass index (P = 0.03) and was the reverse of that expected. CONCLUSIONS: Parentally reported snoring was not independently associated with adverse measurements of metabolic markers, vascular structure or function in 8-year-old children. Parental reports of snoring may be below the treatment threshold without additional diagnosis via sleep studies.
机译：目的：研究儿童打s与心血管危险因素之间的关系。方法：以人群为基础的出生队列的横断面分析，该队列参与了一项预防哮喘的干预措施的随机对照试验，并在8岁时进行了评估。通过父母填写的问卷评估打s的发生和频率。我们测量了广泛的心血管功能标志物，包括非禁食血清脂蛋白，血压，高敏感性C反应蛋白，颈动脉内膜中层厚度（通过超声），肱脉搏波速度和增强指数（通过压平眼压计）。结果：在409名在8岁时进行了打状态评估的儿童中，有321名儿童有血脂，有386名儿童有动脉结构和功能测量。打ing与血压，颈动脉内膜中层厚度或动脉僵硬程度无关（所有P> 0.05）。打频率的增加与较低的高密度脂蛋白胆固醇（-0.032 g / dL /步，95％置信区间-0.060至-0.003）独立相关，尽管打nor者和非打nor者之间高密度脂蛋白的差异不明显（P ＝ 0.052）。打body频率与肱动脉脉搏波速度的关联因体重指数而异（P = 0.03），与预期的相反。结论：父母报告的打与8岁儿童代谢标志物，血管结构或功能的不良测量结果无关。父母打reports的报道可能低于治疗阈值，而没有通过睡眠研究获得额外的诊断。

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