...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Nutritional Science and Vitaminology >The Influence of Iron and Zinc Supplementation on the Bioavailability of Provitamin A Carotenoids from Papaya Following Consumption of a Vitamin A-Deficient Diet
【24h】

The Influence of Iron and Zinc Supplementation on the Bioavailability of Provitamin A Carotenoids from Papaya Following Consumption of a Vitamin A-Deficient Diet

机译：补充铁和锌对食用缺乏维生素A的饮食后番木瓜中原维生素A类胡萝卜素生物利用度的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Iron deficiency anemia, zinc and vitamin A deficiencies are serious public health problems in Cameroon, as in many developing countries. Local vegetables which are sources of provitamin A carotenoids (PACs) can be used to improve vitamin A intakes. However, traditional meals are often unable to cover zinc and iron needs. The aim of this study was to determine the bioavailability of 3 PACs (alpha-carotene, beta-carotene, and beta-cryptoxanthin) in young men, who were fed with a vitamin A-free diet and received iron and zinc supplementation. Twelve healthy participants were divided into three groups and were supplemented with elemental iron (20 mg of iron fumarate), 20 mg of zinc sulfate or iron + zinc (20 mg of iron in the morning and 20 mg of zinc in the evening) for 11 d. They were given a vitamin A- and PAC-free diet from the 6th to the 11th day, followed by a test meal containing 0.55 kg of freshly peeled papaya as a source of PACs. Blood samples were collected four times successively on the 11th day (the test meal day), at TO (just after the test meal), after 2 h (T2), after 4 h (T4) and after 7 h (T7). Ultracentrifugation was used to isolate serum chylomicrons. Retinol appearance and PAC postprandial concentrations were determined. The supplementation with zinc, iron and iron+zinc influenced the chylomicron appearance of retinol and PACs differently as reflected by retention times and maximum absorption peaks. Iron led to highest retinol levels in the chylomicron. Zinc and iron+zinc supplements were best for optimal intact appearance of alpha-carotene, beta-carotene and beta-cryptoxanthin respectively. Supplementation with iron led to the greatest bioavailability of PACs from papaya and its conversion to retinol.
机译：像许多发展中国家一样，铁缺乏症贫血，锌和维生素A缺乏症是喀麦隆的严重公共卫生问题。作为维他命原A类胡萝卜素（PAC）来源的当地蔬菜可用于改善维生素A的摄入量。但是，传统膳食通常无法满足锌和铁的需求。这项研究的目的是确定年轻人中的3种PAC（α-胡萝卜素，β-胡萝卜素和β-隐黄质）的生物利用度，这些男性接受了无维生素A的饮食喂养并接受了铁和锌的补充。将十二名健康参与者分为三组，并补充11种元素铁（20 mg富马酸铁），20 mg硫酸锌或铁与锌（早上20 mg的铁和晚上20 mg的锌）。 d。从第6天到第11天，他们接受了不含维生素A和PAC的饮食，然后是包含0.55公斤新鲜去皮木瓜作为PAC来源的测试餐。在第11天（测试餐日），TO（测试餐后），2小时（T2），4小时（T4）和7小时（T7）之后，连续四次采集血样。使用超速离心分离血清乳糜微粒。测定了视黄醇的外观和餐后PAC的浓度。锌，铁和铁+锌的添加对视黄醇和PAC的乳糜微粒外观的影响不同，这反映在保留时间和最大吸收峰上。铁导致乳糜微粒中视黄醇水平最高。锌和铁+锌补充剂分别是最佳的完整α-胡萝卜素，β-胡萝卜素和β-隐黄质的最佳外观。补充铁导致木瓜中的PAC具有最大的生物利用度，并转化为视黄醇。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号