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Iatrogenic effects of biologics for psoriasis.

机译:生物制剂对牛皮癣的医源性作用。

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摘要

Use of the biologic agents in moderate to severe chronic plaque psoriasis has provided novel and highly efficacious treatment options. Generally less systemically toxic than more traditional agents, the risks and benefits for these agents must also be considered. We present a review of the iatrogenic effects associated with use of the biologic agents in psoriasis. Focus is placed on antitumor necrosis factor agents, because they are the most studied and commonly used agents, as well as T-cell modulators and interleukin inhibitors.
机译:在中度至重度慢性斑块状牛皮癣中使用生物制剂提供了新颖且高效的治疗选择。通常,与更传统的试剂相比,它的系统毒性较小,因此还必须考虑这些试剂的风险和收益。我们提出了与牛皮癣中的生物制剂的使用相关的医源性作用的综述。重点放在抗肿瘤坏死因子药物上,因为它们是研究最多,使用最广泛的药物,以及T细胞调节剂和白介素抑制剂。

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