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首页> 外文期刊>Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs >Urine metabolomics study on the liver injury in rats induced by raw and processed Polygonum multiflorum integrated with pattern recognition and pathways analysis
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Urine metabolomics study on the liver injury in rats induced by raw and processed Polygonum multiflorum integrated with pattern recognition and pathways analysis

机译:模式识别和通路分析相结合的何首乌和炮制何首乌所致大鼠肝损伤的尿代谢组学研究

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摘要

Ethnopharmacological relevance: Polygonum multiflorum L. is a famous traditional Chinese medicine that has always been perceived to be safe. Recently, the increasing case reports on hepatotoxicity induced by Raw P. multiflorum (RP) have attracted particular attention. However, the diagnosis and identification of RP-induced hepatotoxicity are still very difficult for its unknown mechanism and the lack of specific biomarkers.
机译:民族药理意义:何首乌是一种著名的中药,一直被认为是安全的。最近,越来越多的关于生何首乌(RP)引起的肝毒性的病例报道引起了人们的特别关注。然而,由于其未知的机制和缺乏特定的生物标志物,对RP诱导的肝毒性的诊断和鉴定仍然非常困难。

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