首页> 外文期刊>Journal of thoracic imaging >Bronchiolitis obliterans syndrome in lung transplant recipients: correlation of computed tomography findings with bronchiolitis obliterans syndrome stage.
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Bronchiolitis obliterans syndrome in lung transplant recipients: correlation of computed tomography findings with bronchiolitis obliterans syndrome stage.

机译:肺移植受者的闭塞性细支气管炎综合征:计算机断层扫描结果与闭塞性细支气管炎综合征分期的相关性。

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The purpose of this study was to correlate the extent of computed tomographic (CT) findings with the severity of respiratory dysfunction in lung transplant recipients with bronchiolitis obliterans syndrome (BOS). Eighty-nine conventional and 61 thin-section CT scans performed in 44 transplant recipients (17 bilateral, 27 single) with BOS were reviewed for mosaic attenuation, degree of bronchial dilation, bronchial thickening, central and peripheral bronchiectasis, mucus plugging, and air trapping. Findings on conventional and thin-section CT scans were correlated with BOS stage for bilateral and single-lung transplant recipients. In bilateral-lung recipients, a significant correlation existed, although weak, between BOS stage and findings of degree of bronchial dilation (P < 0.01), bronchial wall thickening (P = 0.01), peripheral bronchiectasis (P = 0.01), and mosaic attenuation (P = 0.01) on conventional CT; and bronchial wall thickening (P = 0.01) and mosaic attenuation (P = 0.03) on thin-section CT.In single-lung recipients, BOS stage correlated only with the finding of central bronchiectasis (P = 0.02) on conventional CT scans. No correlation was found between the extent of air trapping and BOS stage in either single- or bilateral-lung transplant recipients. CT findings are relatively poor indices of airflow obstruction in lung transplant recipients with BOS, particularly in those with single-lung transplants for emphysema.
机译:这项研究的目的是将计算机断层扫描(CT)结果的程度与患有闭塞性细支气管炎综合征(BOS)的肺移植接受者的呼吸功能障碍的严重程度相关联。回顾了44例BOS移植受者(17例双侧,27例单侧)进行的89例常规CT扫描和61例薄层CT扫描,以检查其镶嵌衰减,支气管扩张程度,支气管增厚,中央和周边支气管扩张,粘液堵塞和气孔。常规和薄层CT扫描的发现与双侧和单肺移植受者的BOS分期相关。在双肺接受者中,BOS分期与支气管扩张程度(P <0.01),支气管壁增厚(P = 0.01),周围支气管扩张(P = 0.01)和马赛克衰减的发现之间存在显着相关性,尽管微弱。常规CT(P = 0.01);在薄层CT上,支气管壁增厚(P = 0.01)和镶嵌衰减(P = 0.03)。在单肺接受者中,BOS分期仅与常规CT扫描发现的中央支气管扩张有关(P = 0.02)。在单肺或双肺移植受者中,空气滞留的程度与BOS分期之间没有相关性。在有BOS的肺移植受者中,尤其是在有肺气肿的单肺移植患者中,CT表现是相对较差的气流阻塞指标。

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