首页> 外文期刊>Journal of orofacial pain. >Lavage therapy versus nonsurgical therapy for the treatment of arthralgia of the temporomandibular joint: a systematic review of randomized controlled trials.
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Lavage therapy versus nonsurgical therapy for the treatment of arthralgia of the temporomandibular joint: a systematic review of randomized controlled trials.

机译:灌洗疗法与非手术疗法治疗颞下颌关节关节痛:随机对照试验的系统评价。

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摘要

Aims: To carry out a systematic review of randomized controlled trials (RCTs) to investigate in patients with arthralgia of the temporomandibular joint (TMJ) the effectiveness of TMJ lavage compared to nonsurgical treatment with regard to pain intensity and mandibular range of motion. Methods: The electronic databases Cochrane Controlled Trials Register (1960-2012), PubMed÷Medline (1966-2012), and Embase (1966-2012) were systematically searched for relevant RCTs. References of relevant articles were searched for additional studies, as well as citing reports. Two authors independently performed data extraction by using predefined quality indicators. Relevant outcome data included reduction in pain, as assessed by a visual analog scale (VAS) or a pain score, and maximal mouth opening (MMO) before and 6 months after treatment. Included trials were combined using fixed and random effects meta-analysis. Results: Three RCTs (222 patients) were included for meta-analysis. The statistically significant overall standardized mean difference (SMD) (P < .001) with regard to pain intensity was -1.07 (95% CI = -1.38, - 0.76) in favor of TMJ lavage. The MMO did not change significantly (P > .05, SMD = .05 [95% CI = -0.33, 0.23]). Conclusions: The results suggest that lavage of the TMJ may be slightly more effective than nonsurgical treatment for pain reduction. However, this difference is not likely to be clinically relevant.
机译:目的:对随机对照试验(RCT)进行系统评价,以研究颞下颌关节(TMJ)关节痛患者与非手术治疗相比,TMJ灌洗在疼痛强度和下颌运动范围方面的有效性。方法:系统地搜索了电子数据库Cochrane对照试验注册(1960-2012),PubMed÷Medline(1966-2012)和Embase(1966-2012)的相关RCT。搜索相关文章的参考文献以进行其他研究以及引用报告。两位作者使用预定义的质量指标独立执行数据提取。相关结果数据包括通过视觉模拟量表(VAS)或疼痛评分评估的疼痛减轻,以及治疗前后6个月的最大张口(MMO)。纳入的试验采用固定效应和随机效应荟萃分析相结合。结果:纳入3项RCT(222例患者)进行荟萃分析。相对于疼痛强度,统计学上显着的总体标准化平均差异(SMD)(P <.001)为-1.07(95%CI = -1.38,-0.76),有利于TMJ灌洗。 MMO没有显着变化(P> 0.05,SMD = 0.05 [95%CI = -0.33,0.23])。结论:结果表明,TMJ的灌洗可能比非手术治疗减轻疼痛更有效。但是,这种差异在临床上不太可能相关。

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