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Spontaneous Fibrosarcoma in a Djungarian Hamster (Phodopus sungorus).

机译:在Djungarian仓鼠(Phodopus sungorus)中的自发性纤维肉瘤。

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摘要

A 1.5-y-old female Djungarian hamster (Phodopus sungorus) presented with a large subcutaneous mass surrounding the right shoulder. Radiography revealed dislocation of the right humeral articulation and osteolytic lesions of the right scapula. Histologically, the mass was composed of spindle to stellate cells arranged in fascicles interwoven with delicate collagen fibers, and neoplastic cells infiltrated the bone, skeletal muscle, and subcutaneous tissues. Neoplastic cells stained intensely positive for vimentin and negative for S100 protein, neurofilament, and desmin. A minority of neoplastic cells (10% to 20%) stained moderately for smooth muscle actin. The mass was diagnosed as a fibrosarcoma. Although fibrosarcomas are relatively common in dogs and cats, this is the first report of fibrosarcoma in a domestic Djungarian hamster.
机译:一只1.5岁的雌性Djungarian仓鼠(Phodopus sungorus),右肩周围皮下有大量肿块。 X线摄片显示右肱骨关节脱位和右肩cap骨溶骨性病变。从组织学上讲,肿块由纺锤状到星状细胞组成,这些细胞排列在与纤细的胶原纤维交织的纤维束中,而肿瘤细胞则渗入骨骼,骨骼肌和皮下组织。瘤细胞对波形蛋白强烈染色,对S100蛋白,神经丝和结节蛋白染色阴性。少数肿瘤细胞(10%至20%)被中度染色,以显示平滑肌肌动蛋白。该肿块被诊断为纤维肉瘤。尽管纤维肉瘤在猫和狗中相对普遍,但这是首次在家中的仓鼠中纤维肉瘤的报道。

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