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White-coat hypertension

机译:白大衣高血压

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Summary: Numerous studies have examined whether white-coat hypertension (WCHT) is associated with increased cardiovascular risk, but with definitions of WCHT that were not sufficiently robust, results have been inconsistent. The aim of the present review was to standardize the evidence by only including studies that used a definition of WCHT consistent with international guidelines. Published studies were reviewed for data on vascular dysfunction, target organ damage, risk of future sustained hypertension and cardiovascular events. White-coat hypertension has a population prevalence of approximately 15% and is associated with non-smoking and slightly elevated clinic blood pressure. Compared with normotensives, subjects with WCHT are at increased cardiovascular risk due to a higher prevalence of glucose dysregulation, increased left ventricular mass index and increased risk of future diabetes and hypertension. In conclusion, management of a patient with WCHT should focus on cardiovascular risk factors, particularly glucose intolerance, not blood pressure alone.
机译:简介:大量研究检查了白大衣高血压(WCHT)是否与心血管风险增加有关,但是由于WCHT的定义不够充分,结果不一致。本次审查的目的是通过仅包括使用符合国际准则的WCHT定义的研究来标准化证据。对已发表的研究进行了综述,以获取有关血管功能障碍,靶器官损害,未来持续高血压和心血管事件风险的数据。白大衣高血压的人群患病率约为15%,并且与不吸烟和临床血压略有升高有关。与正常血压相比,WCHT患者由于葡萄糖失调的患病率更高,左心室质量指数增加以及将来患糖尿病和高血压的风险增加,因此心血管风险增加。总之,对WCHT患者的治疗应关注心血管危险因素,尤其是葡萄糖耐受不良,而不是单纯的血压。

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