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首页> 外文期刊>Clinical and laboratory haematology >Blood lead levels in iron-deficient and noniron-deficient adults.
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Blood lead levels in iron-deficient and noniron-deficient adults.

机译:缺铁和非缺铁成人的血铅水平。

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摘要

Iron deficiency (ID) has been reported to increase lead absorption. This relationship has been investigated in detail in children but not in adults. This study was designed to investigate whether blood lead levels are significantly higher in iron-deficient adults. ID-parameters (haemoglobin, mean corpuscular volume, mean corpuscular haemoglobin, serum iron, total iron-binding capacity, iron-binding saturation, soluble transferrin receptors, washed zinc protoporphyrin and ferritin) together with whole blood lead were measured in three different adult groups - blood donors (n = 73), pregnant women (n =74) and haemodialysis patients (n = 72). Of a total of 219 subjects tested, 7.7% was found to have a lead level above 10 microg/dl (maximum 16 microg/dl). No association was found between blood lead level and ID [iron-deficient subjects (n: 139), mean: 5.6 microg/dl (SD: 3 microg/dl) and noniron-deficient subjects (n: 80), mean: 5.4 microg/dl (SD: 3 microg/dl)]. The results suggest that the inverse association between blood lead and serum iron in studies carried out on children does not occur in adults.
机译:据报道,铁缺乏症会增加铅的吸收。这种关系已在儿童中进行了详细研究,但在成年人中尚未进行。这项研究旨在调查缺铁成年人的血铅水平是否明显更高。在三个不同的成人组中测量了ID参数(血红蛋白,平均血红蛋白体积,平均血红蛋白血红蛋白,血清铁,总铁结合能力,铁结合饱和度,可溶性转铁蛋白受体,洗净的原卟啉锌和铁蛋白)以及全血铅-献血者(n = 73),孕妇(n = 74)和血液透析患者(n = 72)。在总共219名接受测试的受试者中,发现7.7%的铅水平高于10微克/分升(最大16微克/分升)。在血铅水平和ID之间没有发现关联[缺铁受试者(n:139),平均:5.6 microg / dl(SD:3 microg / dl)和非缺铁受试者(n:80),平均:5.4 microg / dl(SD:3 microg / dl)]。结果表明,在成年人中进行的研究中,血铅与血清铁之间的负相关性并未在成年人中发生。

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