A Catalyst-Enabled Diastereodivergent Aza-Diels-Alder Reaction: Complementarity of N-Heterocyclic Carbenes and Chiral Amines

Rong Zi-Qiang; Wang Min; Chow Chi Hao Eugene; Zhao Yu

首页> 外文期刊>Chemistry: A European journal >A Catalyst-Enabled Diastereodivergent Aza-Diels-Alder Reaction: Complementarity of N-Heterocyclic Carbenes and Chiral Amines

【24h】

A Catalyst-Enabled Diastereodivergent Aza-Diels-Alder Reaction: Complementarity of N-Heterocyclic Carbenes and Chiral Amines

机译：催化剂促成的非对映氮杂-Diels-Alder反应：N-杂环卡宾和手性胺的互补性

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Highly efficient and diastereodivergent aza-Diels-Alder reactions have been developed to access either diastereomeric series of benzofuran-fused delta-lactams and dihydropyridines in nearly perfect stereoselectivity (d.r. > 20: 1, >99% ee for all examples). The complementarity of N-heterocyclic carbene and chiral amine as the catalyst was demonstrated for the first time, together with an excellent level of catalytic efficiency (1 mol% loading).

机译：已开发出高效且非对映异构的aza-Diels-Alder反应，以接近完美立体选择性的方式获得苯并呋喃稠合的δ-内酰胺和二氢吡啶的非对映异构系列（对于所有示例，d.r。> 20：1，> 99％ee）。首次证明了N-杂环卡宾和手性胺作为催化剂的互补性，以及优异的催化效率（1 mol％的负载量）。

著录项

来源
《Chemistry: A European journal》 |2016年第28期|共5页
作者
Rong Zi-Qiang; Wang Min; Chow Chi Hao Eugene; Zhao Yu;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
chiral amines; Diels-Alder cycloaddition; diastereodivergence; enantioselectivity; N-heterocyclic carbenes;

机译：手性胺;Diels-Alder环加成;非对映异构;对映选择性;N-杂环卡宾;

相似文献

外文文献
中文文献
专利

1. A Catalyst-Enabled Diastereodivergent Aza-Diels-Alder Reaction: Complementarity of N-Heterocyclic Carbenes and Chiral Amines [J] . Rong Zi-Qiang, Wang Min, Chow Chi Hao Eugene, Chemistry: A European journal . 2016,第28期

机译：催化剂促成的非对映氮杂-Diels-Alder反应：N-杂环卡宾和手性胺的互补性
2. N-Heterocyclic Carbenes: VI. Abietane-Based Chiral Benzimidazolium Salts as N-Heterocyclic Carbene Ligands in the Heck Reaction [J] . V. A. Glushkov, E. N. Teplykh, M. S. Denisov Russian Journal of Organic Chemistry . 2012,第6期

机译：N-杂环卡宾：VI。基于Abietane的手性苯并咪唑鎓盐作为Heck反应中的N-杂环碳原子配体
3. Metal-mediated asymmetric alkylation using chiral N-heterocyclic carbenes derived from chiral amines [J] . Richard E. Douthwaite Coordination chemistry reviews . 2007,第5a6期

机译：使用手性胺衍生的手性N-杂环卡宾进行金属介导的不对称烷基化
4. Ruthenium–Indenylidene Complexes Bearing Saturated N-Heterocyclic Carbenes: Synthesis and Application in Ring-Closing Metathesis Reactions [C] . Stijn Monsaert, Els De Canck, Renata Drozdzak, NATO Advanced Study Institute on Green Metathesis Chemistry: Great Challenges in Synthesis, Catalysis and Nanotechnology . 2010

机译：含饱和N-杂环的钌 - 茚基三苯基复合物：在闭环复分解反应中的合成和应用
5. 1. Axially-chiral 7-membered N-heterocyclic carbenes: Synthesis and application to palladium-catalyzed intramolecular aerobic oxidation of olefins 2. Development of palladium-catalyzed aerobic oxidative olefin amination reactions [D] . Scarborough, Christopher C. 2008

机译：1.轴向手性7元N-杂环卡宾：烯烃的钯催化分子内需氧氧化的合成及应用2.钯催化需氧氧化烯烃胺化反应的发展
6. Organocatalysis Special Feature: Chiral N-heterocyclic carbene-catalyzed generation of ester enolate equivalents from αβ-unsaturated aldehydes for enantioselective Diels–Alder reactions [O] . Juthanat Kaeobamrung, Marisa C. Kozlowski, Jeffrey W. Bode 2010

机译：有机催化特性：手性N-杂环卡宾催化从αβ-不饱和醛生成烯醇酯等效物用于对映选择性Diels-Alder反应
7. Back Cover: A Catalyst-Enabled Diastereodivergent Aza-Diels-Alder Reaction: Complementarity ofN-Heterocyclic Carbenes and Chiral Amines (Chem. Eur. J. 28/2016) [O] . Zi-Qiang Rong, Min Wang, Chi Hao Eugene Chow, 2016

机译：返回盖子：使催化剂的非映异构化AZA-Diels-Alder反应：互补性α-杂环碳切割和手性胺（Chem.Eur。J. 28/2016）

A Catalyst-Enabled Diastereodivergent Aza-Diels-Alder Reaction: Complementarity of N-Heterocyclic Carbenes and Chiral Amines

摘要

著录项

相似文献

相关主题

期刊订阅