Combinatorial synthesis and biological evaluations of (E)-beta-trifluoromethyl vinylsulfones as antitumor agents

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Combinatorial synthesis and biological evaluations of (E)-beta-trifluoromethyl vinylsulfones as antitumor agents

机译：（e）-beta-三氟甲基乙烯基砜作为抗肿瘤剂的组合合成及生物学评价

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Combinatorial synthesis of (E)-beta-trifluoromethyl vinylsulfones is accomplished through a reaction of alkynes, Togni reagent, and sodium benzenesulfinates in DMSO under metal-free conditions at room temperature. These compounds are evaluated in several assays against different tumor cells. Some hits are identified against ES-2, HO-8910, and K562.

机译：（e）-beta-三氟甲基乙烯基的组合合成通过炔烃，Togni试剂和苯磺酸钠在室温下的无金属条件下在DMSO中的反应完成。这些化合物在针对不同肿瘤细胞的几种测定中评价。一些命中针对ES-2，HO-8910和K562识别。

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《RSC Advances》 |2019年第54期|共9页
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1. Combinatorial synthesis and biological evaluations of (E)-beta-trifluoromethyl vinylsulfones as antitumor agents [J] . RSC Advances . 2019,第54期

机译：（e）-beta-三氟甲基乙烯基砜作为抗肿瘤剂的组合合成及生物学评价
2. Antitumor agents. 181. Synthesis and biological evaluation of 6,7,2',3',4'-substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a new class of antimitotic antitumor agents. [J] . Xia Y, Yang ZY, Xia P, Journal of Medicinal Chemistry . 1998,第7期

机译：抗肿瘤药。 181.6,7,2'，3'，4'-取代的1,2,3,4,4-四氢-2-苯基-4-喹诺酮类化合物作为一类新型抗有丝分裂抗肿瘤剂的合成及生物学评价。
3. Antitumor Agents. 266. Design, Synthesis, and Biological Evaluation of Novel 2-(Furan-2-yl)naphthalen-1-ol Derivatives as Potent and Selective Antibreast Cancer Agents [J] . Dong YZ, Shi Q, Liu YN, Journal of Medicinal Chemistry . 2009,第11期

机译：抗肿瘤剂。 266.作为有效和选择性抗乳腺癌药物的新型2-（呋喃-2-基）萘-1-醇衍生物的设计，合成和生物学评估
4. Synthesis and biological evaluation of the novel antitumor agent 3'-monosubstituted chalcone derivatives [C] . Luyao Wang, Hongye Zhao, Dan Wu, International Conference on Material, Mechanical and Manufacturing Engineering . 2015

机译：新型抗肿瘤剂的合成与生物学评价3'-单取代的硫酮衍生物
5. Synthesis of macrocycles and their biological evaluation as antitumor and antibacterial agents. [D] . Pan, Po-Shen. 2008

机译：大环化合物的合成及其作为抗肿瘤和抗菌剂的生物学评估。
6. Antitumor Agents 266*. Design Synthesis and Biological Evaluation of Novel 2-(Furan-2-yl) naphthalen-1-ol Derivatives as Potent and Selective Anti-Breast Cancer Agents [O] . Yizhou Dong, Qian Shi, Yi-Nan Liu, -1

机译：抗肿瘤药物266 *。新颖的设计合成和生物学评价2-（呋喃-2-基）萘-1-醇衍生物作为有效且选择性的抗乳腺癌试剂
7. Antitumor Agents. 254. Synthesis and Biological Evaluation of Novel Neo-tanshinlactone Analogues as Potent Anti-Breast Cancer Agents [O] . -1

机译：抗肿瘤剂。 254.新型新丹参酮内酯类似物的合成和生物学评价为有效的抗乳腺癌药剂

Combinatorial synthesis and biological evaluations of (E)-beta-trifluoromethyl vinylsulfones as antitumor agents

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