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首页> 外文期刊>Current Science: A Fortnightly Journal of Research >Fundamental genomic unity of ethnic India is revealed by analysis of mitochondrial DNA
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Fundamental genomic unity of ethnic India is revealed by analysis of mitochondrial DNA

机译：通过分析线粒体DNA，揭示了印度民族的基本基因组统一性

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摘要

Mitochondrial DNA (mtDNA) profiles of 23 ethnic populations of India drawn from diverse cultural, linguistic and geographical backgrounds are presented. There is extensive sharing of a small number of mtDNA haplotypes, reconstructed on the basis of restriction fragment length polymorphisms, among the populations. This indicates that Indian populations were founded by a small number of females, possibly arriving on one of the early waves of out-of-Africa migration of modern humans; ethnic differentiation occurred subsequently through demographic expansions and geographic dispersal, The Asian-specific haplogroup M is in high frequency in most populations, especially tribal populations and Dravidian populations of southern India, Populations in which the frequencies of haplogroup M are relatively lo M ef show higher frequencies of haplogroup U; such populations are primarily caste populations of northern India. This finding is indicative of a higher Caucasoid admixture in northern Indian populations. By examining the sharing of haplotypes between Indian and south-east Asian populations, we have provided evidence that south-east Asia was peopled by two waves of migration, one originating in India and the other originating in southern China. These findings have been examined and interpreted in the light of inferences derived from previous genomic and historical studies. [References: 44]
机译：介绍了来自不同文化，语言和地理背景的印度23个种族的线粒体DNA（mtDNA）概况。在人群中，根据限制性片段长度多态性重建的少数mtDNA单倍型存在广泛共享。这表明印度人口是由少数女性建立的，可能是在现代人从非洲外迁的早期浪潮中之一到达的。随后通过人口扩展和地理分散发生种族分化。大多数亚洲人口，特别是印度南部的部落人口和德拉维人人口，亚洲特定的单倍群M出现频率较高，单倍群M的频率相对较低的人群表现出较高的频率。单倍群U的频率;这些人口主要是印度北部的种姓人口。这一发现表明印度北部人口中的高加索混合物含量更高。通过研究印度人与东南亚人口之间的单体型共享，我们提供了证据，表明东南亚是由两次移民浪潮占领的，其中一次移民起源于印度，另一次起源于中国南部。根据以前的基因组和历史研究得出的推论，对这些发现进行了检查和解释。 [参考：44]

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