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Evening preference is related to the incidence of depressive states independent of sleep-wake conditions

机译:晚上偏好与抑郁状态的发生率有关,而与抑郁状态无关

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Although evening preference has recently been identified as a risk factor for depression, it has not been substantiated whether evening preference is a direct risk factor for depressive states, or if it is associated secondarily through other factors, such as delayed sleep timing and shortened sleep duration. The objective of this study is to investigate associations in Japanese adult subjects between evening preference and incidence of depressive states, adjusting for various sleep parameters related to depressive states. The Morningness-Eveningness Questionnaire (MEQ), the Pittsburgh Sleep Quality Index (PSQI), and the Center for Epidemiologic Studies Depression Scale (CES-D) were administered to 1170 individuals (493 males/677 females; mean and range 38.5 and 20-59 yrs) to assess their diurnal preferences, sleeping states, and presence of depression symptoms. Subjects were classified into five chronotypes based on MEQ scores. Evening preference was associated with delayed sleep timing, shortened sleep duration, deteriorated subjective sleep quality, and worsened daytime sleepiness. Logistic regression analysis demonstrated that the extreme evening type (odds ratio [OR] = 1.926, p = .018) was associated with increased incidence of depressive states and that the extreme morning type (OR = 0.342, p = .038) was associated with the decreased incidence of depressive states, independent of sleep parameters, such as nocturnal awakening (OR = 1.844, p<.001), subjective sleep quality (OR = 2.471, p<.001), and daytime sleepiness (OR = 1.895, p < .001). However, no significant associations were observed between the incidence of depressive states and sleep duration, sleep timing, and sleep debt (levels of insufficient sleep). Although the findings of this study do not demonstrate a causative relationship between evening preference and depression, they do suggest the presence of functional associations between mood adjustment and biological clock systems that regulate diurnal preference. They also suggest that evening preference might increase susceptibility to the induction of mood disorders.
机译:尽管最近已将傍晚偏好确定为抑郁症的危险因素,但尚无证据证实傍晚偏好是否是抑郁状态的直接危险因素,或者其次是与其他因素(例如延迟的睡眠时间和缩短的睡眠时间)相关联。这项研究的目的是调查日本成年受试者夜间偏好与抑郁状态发生之间的关联,并调整与抑郁状态有关的各种睡眠参数。早晨-晚上问卷(MEQ),匹兹堡睡眠质量指数(PSQI)和流行病学研究中心抑郁量表(CES-D)被施用于1170例患者(493名男性/ 677名女性;平均范围为38.5和20- 59岁)来评估他们的昼夜喜好,睡眠状态和抑郁症状的存在。根据MEQ分数将受试者分为五种表型。晚上偏爱与延迟的睡眠时间,缩短的睡眠时间,恶化的主观睡眠质量和恶化的白天嗜睡有关。 Logistic回归分析表明,极端夜间类型(OR = 1.926,p = .018)与抑郁状态的发生率相关,而极端早晨类型(OR = 0.342,p = .038)与抑郁状态的发生率相关抑郁状态的发生率降低,与睡眠参数无关,例如夜间觉醒(OR = 1.844,p <.001),主观睡眠质量(OR = 2.471,p <.001)和白天嗜睡(OR = 1.895,p <.001)。但是,在抑郁状态的发生率与睡眠时间,睡眠时间和睡眠负担(睡眠不足水平)之间没有发现显着相关性。尽管这项研究的结果并未证明夜间偏爱与抑郁之间存在因果关系,但确实暗示了情绪调节与调节昼夜偏爱的生物钟系统之间存在功能关联。他们还建议,夜间偏好可能会增加诱发情绪障碍的敏感性。

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