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首页> 外文期刊>Clinical and experimental allergy : >Confirmed prevalence of food allergy and non-allergic food hypersensitivity in a Mediterranean population.
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Confirmed prevalence of food allergy and non-allergic food hypersensitivity in a Mediterranean population.

机译：确认在地中海人口中食用过敏和非过敏性食物过敏的患病率。

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BACKGROUND: Until the present, no comprehensive studies evaluating the prevalence of food allergy and non-allergic food hypersensitivity (FA/NAFH) in adults have been done in Turkey or its surrounding countries. OBJECTIVE: This large population-based study was planned to identify the confirmed prevalence of adverse reactions to food in adults in Istanbul. METHODS: A total of 17 064 telephone numbers were randomly selected from both the European and Asian sides of Istanbul, and the 11 816 subjects who agreed to participate in the study were addressed with a questionnaire of eight items. Those who disclosed food-related complaints in this survey were called again and a similar questionnaire was repeated. The respondents who were suspected of having food allergy or food hypersensitivity were invited for a personal clinical investigation that included double-blind, placebo-controlled food challenge tests. RESULTS: The lifetime prevalence of self-reported FA/NAFH was found to be 9.5% [1118/11 816; 95% confidence interval (CI): 8.94-10.00%]. After the clinical investigations, the point prevalence of FA/NAFH, which also included the 'possible FA/NAFH group', was found to be as low as 0.3% (30/11 816; 95% CI: 0.17-0.36%), and the FA/NAFH rates assessed by double-blind, placebo-controlled food challenge tests were 0.1% (12/11 816; 95% CI: 0.05-0.18%) and 0.1% (11/11 816; 95% CI: 0.05-0.17%), respectively. The most significant factor influencing FA/NAFH was familial atopy (adjusted OR 4.3; 95% CI: 3.67-4.99), and the most related atopic disease was itching dermatitis/urticaria (adjusted OR: 3.9; 95% CI: 3.31-4.54). CONCLUSION: We may conclude that FA/NAFH in the Turkish population seems to be low when compared with Northern and Western European countries. This may be due to genetic, cultural or dietary factors, and further studies evaluating the reasons for this low prevalence of FA/NAFH in our population are needed.
机译：背景：直到目前，土耳其或其周边国家没有评估成人的食物过敏和非过敏性食物超敏反应（FA / NAFH）的普遍研究。目的：计划这项基于大量的学习，旨在确定伊斯坦布尔成人食品不良反应的确认患病率。方法：共有17个064个电话号码从伊斯坦布尔的欧洲和亚洲双方随机选中，同意参加该研究的11个816个受试者被八项调查问卷解决。那些披露了在本调查中披露的食物有关的投诉，并重复了类似的调查问卷。被邀请怀疑患有食物过敏或食物超敏反应的受访者进行个人临床调查，包括双盲，安慰剂对照的食物挑战测试。结果：发现自我报告的FA / NAFH的寿命流行为9.5％[1118/11 816; 95％置信区间（CI）：8.94-10.00％]。在临床调查之后，发现FA / NAFH的点普遍率包括“可能的FA / NAFH集团”，发现低至0.3％（30/11 816; 95％CI：0.17-0.36％），和双盲，安慰剂对照食品挑战试验评估的FA / NAFH率为0.1％（12/11 816; 95％CI：0.05-0.18％）和0.1％（11/11 816; 95％CI：0.05分别为-0.17％）。影响FA / NAFH的最重要因素是家族特性（调整或4.3; 95％CI：3.67-4.99），最相关的特征性疾病瘙痒皮炎/荨麻疹（调整或：3.9; 95％CI：3.31-4.54） 。结论：与北部和西欧国家相比，土耳其人口中的FA / NAFH似乎很低。这可能是由于遗传，文化或饮食因素，还需要进一步研究，评估我们人口中FA / NAFH的这种低普遍性的原因。

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