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首页> 外文期刊>Current women’s health reviews >Prevalence of Latent Tuberculosis (LTB) Among Pregnant Women in a High Burden Setting in Sudan using Interferon Gamma (IFN- γ) Releasing Assay (IGRA)
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Prevalence of Latent Tuberculosis (LTB) Among Pregnant Women in a High Burden Setting in Sudan using Interferon Gamma (IFN- γ) Releasing Assay (IGRA)

机译：使用干扰素γ（ICN-γ）苏丹苏丹高负荷设定妇女潜伏妇女潜伏期患病率（IGRA）

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Background: Accurate timing for diagnosis and treatment of latent tuberculosis (LTB) isimportant to reduce morbidity and mortality for both mother and child.Objectives: To investigate the prevalence rate of LTB and its associated factors during pregnancyusing gamma interferon (IFN- γ) release assay (IGRA).Methods: A cross-sectional facility-based study carried out in Kassala hospital, Eastern Sudan betweenJanuary and March 2015.Results: Two hundred and forty-nine women were enrolled in this study and 18.1% (45/249) hadconfirmed positive for M. tuberculosis infection using IGRA. The mean age, parity and gestationalage of the LTB patients were 29.6 (4.4), 2.2 (1.2) and 21.9 (8.8), respectively. The vast majority ofthese patients was of rural residence (72.7%), housewives (91.1%) and illiterate (73.3%). More thanhalf (25, 55.6%) gave a history of contact with tuberculosis patients, 26.7% (12/45) were vaccinatedand 11.1% (5/45) had a medical history of diabetes mellitus. In logistic regression model, while age,parity, education, occupation, size of family members, smoking, BCG status and medical history ofdiabetes mellitus were not associated with latent tuberculosis during pregnancy, history of contactwith TB patients (OR=13.5; CI=5.6 to 32.5; P<0.001) and rural residence (OR=0.3; CI=0.1 to 0.7;P=0.006) was significantly correlated to LTB in pregnancy.Conclusion: Thus, screening of all pregnant women living in high burden setting of tuberculosis isrecommended even in the absence of overt clinical signs of the disease.
机译：背景：潜伏性结核病（LTB）isimportant的诊断和治疗的精确定时，以减少发病率和死亡率对母亲和child.Objectives：要pregnancyusingγ干扰素（IFN-γ）释放测定法期间调查LTB和其相关因素的患病率（IGRA）方法：机构为基础的横断面研究卡萨拉医院进行，苏丹东部betweenJanuary三月2015.Results：200名和49的女性研究对象和18.1％（45/249）hadconfirmed对结核分枝杆菌感染使用IGRA阳性。的LTB患者的平均年龄，奇偶校验和gestationalage分别为29.6（4.4），2.2（1.2）和21.9（8.8），分别。绝大多数患者ofthese是农村居民（72.7％），家庭主妇（91.1％）和文盲（73.3％）的。更多thanhalf（25岁，55.6％）给出了与肺结核病人接触史，26.7％（12/45）为vaccinatedand 11.1％（5/45）有糖尿病病史。在逻辑回归模型，而年龄，胎次，文化程度，职业，家庭成员，吸烟，BCG状况和病史ofdiabetes糖尿病的大小并没有怀孕期间潜伏性结核病，contactwith结核病患者的病史（OR = 13.5关联; CI = 5.6到32.5; P <0.001）和农村居民（OR = 0.3; CI = 0.1〜0.7; P = 0.006）中的溶液显著相关LTB在pregnancy.Conclusion：因此，筛选生活在结核病高负担设置所有孕妇的isrecommended即使在没有疾病的明显临床症状。

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