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Comparing immediate-type food allergy in humans and companion animalsrevealing unmet needs

机译：比较人类和伴侣动物的立即型食物过敏，揭示未满足的需求

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Adverse food reactions occur in human as well as veterinary patients. Systematic comparison may lead to improved recommendations for prevention and treatment in both. In this position paper, we summarize the current knowledge on immediate-type food allergy vs other food adverse reactions in companion animals, and compare this to the human situation. While the prevalence of food allergy in humans has been well studied for some allergens, this remains to be investigated for animal patients, where owner-reported as well as veterinarian-diagnosed food adverse reactions are on the increase. The characteristics of the disease in humans vs dogs, cats, and horses are most often caused by similar, but sometimes species-dependent different pathophysiological mechanisms, prompting the specific clinical symptoms, diagnoses, and treatments. Furthermore, little is known about the allergen molecules causative for type I food allergy in animals, which, like in human patients, could represent predictive biomarkers for risk evaluation. The definite diagnosis of food allergy reliesas in humanson elimination diet and provocation tests. Besides allergen avoidance in daily practice, novel treatment options and tolerization strategies are underway. Taken together, numerous knowledge gaps were identified in veterinary food allergy, which need to be filled by systematic comparative studies.
机译：在人类以及兽医患者中发生不良食物反应。系统比较可能导致改进两者预防和治疗的建议。在这个位置纸中，我们总结了目前关于立即型食品过敏的知识与伴侣动物中的其他食物不良反应，并将其与人体情况进行比较。虽然对人类的食物过敏的患病率已经很好地研究了一些过敏原，但这对于动物患者来说，这仍有待研究的，其中所有者报告的和兽医诊断的食物不良反应增加。人类疾病的特征与狗，猫和马匹的疾病最常是相似的，但有时物种依赖性不同的病理生理机制，促使特定的临床症状，诊断和治疗。此外，关于I型食物过敏的造成的过敏原分子知之甚少，类似于人类患者，这可能代表风险评估的预测生物标志物。人对消除饮食饮食和挑衅试验中食物过敏依赖的明确诊断。除了在日常实践中避免过敏原，还在进行新的治疗方案和耐受性战略。在一起，在兽医食物过敏中确定了许多知识间隙，需要通过系统的比较研究填充。

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