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首页> 外文期刊>Annual review of cell and developmental biology >Specialized Intercellular Communications via Cytonemes and Nanotubes
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Specialized Intercellular Communications via Cytonemes and Nanotubes

机译：通过休闲和纳米管专用细胞间通信

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摘要

In recent years, thin membrane protrusions such as cytonemes and tunneling nanotubes have emerged as a novel mechanism of intercellular communication. Protrusion-based cellular interactions allow for specific communication between participating cells and have a distinct spectrum of advantages compared to secretion-and diffusion-based intercellular communication. Identification of protrusion-based signaling in diverse systems suggests that this mechanism is a ubiquitous and prevailing means of communication employed by many cell types. Moreover, accumulating evidence indicates that protrusion-based intercellular communication is often involved in pathogenesis, including cancers and infections. Here we review our current understanding of protrusion-based intercellular communication.
机译：近年来，薄膜突起（如乌腹和隧道纳米管）被出现为细胞间通信的新机制。 基于突出基的蜂窝相互作用允许参与细胞之间的特定通信，与分泌和扩散的细胞间通信相比具有不同的优点。 不同系统中基于突出信号传导的识别表明，这种机制是许多细胞类型采用的普遍存存的通信手段。 此外，累积证据表明突出基的细胞间通信通常涉及发病机制，包括癌症和感染。 在这里，我们审查了对基于突出的细胞间通信的了解。

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