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Nanostructured lipid carriers (NLC) in cosmetic dermal products.

机译:化妆品皮肤产品中的纳米结构脂质载体(NLC)。

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摘要

The first generation of lipid nanoparticles was introduced as solid lipid nanoparticles (SLN), the second, improved generation as nanostructured lipid carriers (NLC). Identical to the liposomes, the lipid nanoparticles (NLC) appeared as products first on the cosmetic market. The article gives an overview of the cosmetic benefits of lipid nanoparticles, that means enhancement of chemical stability of actives, film formation, controlled occlusion, skin hydration, enhanced skin bioavailability and physical stability of the lipid nanoparticles as topical formulations. NLC are on the market as concentrates to be used as cosmetic excipients, special formulation challenges for these products are discussed. NLC appeared also in a number of finished cosmetic products world-wide. An overview of these products is provided including their special effects due to the lipid nanoparticles, lipids used for their production and incorporated cosmetic actives.
机译:第一代脂质纳米颗粒作为固体脂质纳米颗粒(SLN)引入,第二代改良纳米颗粒作为纳米结构脂质载体(NLC)引入。与脂质体相同,脂质纳米颗粒(NLC)作为化妆品首次出现在化妆品市场上。本文概述了脂质纳米颗粒的美容益处,这意味着可以增强局部制剂形式的脂质纳米颗粒的化学稳定性,成膜性,可控的咬合,皮肤水合作用,增强的皮肤生物利用度和物理稳定性。 NLC以浓缩物的形式用作化妆品赋形剂,讨论了这些产品的特殊配方挑战。 NLC还出现在世界各地的许多化妆品成品中。提供了这些产品的概述,包括由于脂质纳米颗粒,用于其生产的脂质和掺入的化妆品活性物质而产生的特殊效果。

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