Diagnostic utility of an age‐specific cut‐off for d‐dimer for pulmonary embolism assessment when used with various pulmonary embolism risk scores

Ackerly Imogen; Klim Sharon; McFarlane James; Kelly Anne‐Maree

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Diagnostic utility of an age‐specific cut‐off for d‐dimer for pulmonary embolism assessment when used with various pulmonary embolism risk scores

机译：用于肺栓塞评估的D-二聚体的年龄特异性截止的诊断效用（用于各种肺栓塞风险评分

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Abstract This retrospective cohort study compared the diagnostic utility (sensitivity, specificity and negative predictive value (NPV)) of the age‐times‐10 adjusted d‐dimer cut‐off used in combination with the original and simplified Well's pulmonary embolism (PE) scores and the original and simplified revised Geneva scores to identify patients in whom PE is classified as unlikely according to each score. The PE risk scores performed similarly with high sensitivity (97.6, 97.1, 96.9 and 97.1% respectively) and NPV (99.3, 99.3, 99.2 and 99.2% respectively). Each missed only one PE. The age‐times‐10 age‐adjusted d‐dimer assay cut‐off performed similarly with each of the clinical risk scores tested with high sensitivity and NPV.

机译：摘要这种回顾性队列研究比较了诊断效用（次次调节D-二聚体截止的诊断用途（敏感性，特异性和负面预测值（NPV）与原始和简体井的肺栓塞（PE）分数组合使用而原始的和简化修订的日内瓦分数识别PE的患者根据每个分数不太可能。体育风险评分与高灵敏度相似（97.6,97.1,96.9和97.1％）和NPV（分别为99.3,99.3,99.2和99.2％）。每个人都错过了一个pe。时代-10岁的年龄调节的D-二聚体测定与具有高灵敏度和NPV的每个临床风险分数相似。

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来源
《Internal medicine journal》 |2018年第4期|共4页
作者
Ackerly Imogen; Klim Sharon; McFarlane James; Kelly Anne‐Maree;
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作者单位

Western Health and Joseph Epstein Centre for Emergency Medicine Research at Western HealthSunshine;

Joseph Epstein Centre for Emergency Medicine Research at Western HealthMelbourne Victoria Australia;

Department of Emergency MedicineFootscray HospitalMelbourne Victoria Australia;

Joseph Epstein Centre for Emergency Medicine Research at Western HealthMelbourne Victoria Australia;

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原文格式 PDF
正文语种 eng
中图分类内科学;
关键词
pulmonary embolism; risk scores; d‐dimer; age;

机译：肺栓塞;风险分数;D-二聚体;年龄;

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1. Diagnostic utility of an age‐specific cut‐off for d‐dimer for pulmonary embolism assessment when used with various pulmonary embolism risk scores [J] . Ackerly Imogen, Klim Sharon, McFarlane James, Internal medicine journal . 2018,第4期

机译：用于肺栓塞评估的D-二聚体的年龄特异性截止的诊断效用（用于各种肺栓塞风险评分
2. Utility of Inferior Vena Cava Filters in Severe Pulmonary Embolism, Catheter-directed Therapy in Massive and Submassive Pulmonary Embolism, and HAS-BLED Score to Determine Risk of Major Hemorrhage in Pulmonary Embolism [J] . Anish K. Desai, Joyce Pang, Malaygiri Aparnath, American journal of respiratory and critical care medicine . 2016,第11期

机译：下腔静脉滤器在严重肺栓塞，大规模和亚大规模肺栓塞的导管导向治疗以及HAS-BLED评分确定肺栓塞大出血风险中的效用
3. Comparison of high specificity with standard versions of a quantitative latex D-dimer test in the assessment of community pulmonary embolism: HaemosIL D-dimer HS and pulmonary embolism. [J] . Than MP, Helm J, Calder K Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2009,第2期

机译：在评估社区肺栓塞：HaemosIL D-二聚体HS和肺栓塞中，将高特异性与定量乳胶D-二聚体测试的标准版本进行比较。
4. A Lung Graph-Model for Pulmonary Hypertension and Pulmonary Embolism Detection on DECT Images [C] . Yashin Dicente Cid, Henning Muller, Alexandra Platon, International Workshop on Medical Computer Vision: Algorithms for Big Data . 2017

机译：DECT图像肺动脉高压和肺栓塞检测的肺图模型
5. Research management of new drug development: A feasibility study of the development of a fixed combination of DHE and heparin for the prophylaxis of postoperative deep vein thrombosis and pulmonary embolism. [D] . DiSerio, Frank Joseph. 1979

机译：新药开发的研究管理：开发DHE和肝素固定组合以预防术后深静脉血栓形成和肺栓塞的可行性研究。
6. d-Dimer Assessment Improves the Simplified Pulmonary Embolism Severity Index for In-Hospital Risk Stratification in Acute Pulmonary Embolism [O] . Marta Kozlowska, Magdalena Plywaczewska, Marcin Koc, 2018

机译：d-二聚体评估提高了简化的肺栓塞严重度指数用于急性肺栓塞的院内风险分层
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Diagnostic utility of an age‐specific cut‐off for d‐dimer for pulmonary embolism assessment when used with various pulmonary embolism risk scores

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