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首页> 外文期刊>Schizophrenia research >Predictors of recovery from psychosis Analyses of clinical and social factors associated with recovery among patients with first-episode psychosis after 5 years.
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Predictors of recovery from psychosis Analyses of clinical and social factors associated with recovery among patients with first-episode psychosis after 5 years.

机译：5年后患者复苏患者临床和社会因素恢复的预测因素。

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INTRODUCTION: This paper aims to investigate the predictors of good outcome after first-episode non-affective psychosis and the clinical and social trajectories of those that recover. METHODS: A cohort of 255 patients with first-episode non-affective psychosis was interviewed 5 years after first diagnosis and treatment. Recovery was defined as working or studying, having a GAF-function score of 60 or above, having remission of negative and psychotic symptoms, and not living in a supported housing facility or being hospitalized during the last 2 years before the five-year follow-up interview. RESULTS: A total of 40 (15.7%) were found to be recovered, and 76 (29.8%) had a job or were studying after 5 years. Of those working, as many as 20 still had psychotic symptoms. Also notable is that out of the 40 recovered, less than half were recovered after 2 years. Recovery after 5 years was predicted by female sex (OR 2.4, 95% CI 1.0-5.8), higher age (OR 0.91, 95% CI 0.83-0.99), pre-morbid social adaptation (OR 0.72, 95% CI 0.56-0.93), growing up with both parents (OR 2.6, 95% CI 1.0-6.8) and low level of negative symptoms (OR 0.51, 95% CI 0.33 to 0.77) at baseline. DISCUSSION: Our findings suggest that a stable social life with normal social functioning has a predictive value for good outcome. These measures might be influenced by negative symptoms, but in the multivariate analysis with negative symptoms included they have an independent effect. Also our findings suggest that, after first-episode psychosis, some patients can still experience psychotic symptoms, but have a job and a fairly stable life.
机译：介绍：本文旨在调查首发非情感精神病后良好结果的预测因素，以及恢复的人的临床和社会轨迹。方法：在第一次诊断和治疗后5年后采访了255名患有非情感精神病的255名患者。恢复被定义为工作或学习，具有60或以上的GAF函数得分，重息负面和精神病症状，而不是在五年后的过去2年内住院或住院在五年之后 - 面试。结果：发现共有40名（15.7％）收回，76名（29.8％）有工作或在5年后学习。那些工作的人，多达20个仍有精神症状。值得注意的是，在40次回收中，2年后恢复不到一半。恢复5年后由女性预测（或2.4,95％CI 1.0-5.8），年龄较高（或0.91,95％CI 0.83-0.99），导病前的社会适应（或0.72,95％CI 0.56-0.93 ），在基线时，与父母（或2.6,95％CI 1.0-6.8）和低水平的阴性症状（或0.51,95％CI 0.33至0.77）一起延长。讨论：我们的研究结果表明，具有正常社会功能的稳定社会生活具有良好结果的预测价值。这些措施可能受到阴性症状的影响，但在多变量分析中，包括阴性症状，它们具有独立效果。我们的研究结果表明，在第一集发作精神病后，一些患者仍然可以体验精神症状，但有一份工作和相当稳定的生活。

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