首页> 外文期刊>The Journal of Antibiotics: An International Journal >A cryptic antibiotic triggered by monensin.
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A cryptic antibiotic triggered by monensin.

机译:由宫蛋白引发的隐秘抗生素。

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摘要

Recently, we reported the identification of promomycin, a new polyether closely related to lonomycin, based on its activity inducing antibiotic production in some Streptomyces spp.1 Originally, we discovered that promomycin produced by Streptomyces scabrisporus strain 153 promoted antibiotic production in Streptomyces griseorubiginosus srain 574, but we also revealed that other polyethers including monensin exert similar stimulatory effects on antibiotic production. Promomycin and monensin exhibit antibacterial activity by themselves due to the function as ionophores,1'2 but we observed that they stimulated antibiotic production in some Streptomyces spp.
机译:最近,我们报告了幼苗霉素的鉴定,一种与丽芳霉素密切相关的新聚醚,基于其活性诱导抗生素产量在一些链霉菌SPP.1中,我们发现由Streptomyces scabrisporus菌株153培养的突出菌霉素促进抗生素生产GriseRumonyces griseorubiginosus srain 574 但是,我们还透露,其他聚醚在包括宫蛋白潜行的刺激性对抗生素生产产生类似的刺激作用。 普雷莫霉素和宫蛋白由于作为离子团的功能而表现出抗菌活性,但是我们观察到它们在一些链霉菌SPP中刺激抗生素产生。

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