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Oregonensins A and B, new meroterpenoids from the culture broth of Ganoderma oregonense and their antioxidant activity

机译:来自灵芝甲肾上腺素培养的新梅特萜类化合物和抗氧化剂活性

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摘要

Two new meroterpene derivatives (1 and 2), together with three known compounds (3-5) were isolated from the culture broth of fungus Ganoderma oregonense. Chemical structures of compounds 1-5 were determined using spectroscopic methods. All compounds were tested for 2,2 '-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging efficacy. Compound 1 exhibited significant antioxidant activities with IC50 values of 31.2 and 65.4 mu M in the ABTS and DPPH radical scavenging activities, respectively.
机译:两种新的梅特培养衍生物(1和2)与三种已知的化合物(3-5)一起与真菌灵芝甲鼻酮的培养液中分离出来。 使用光谱法测定化合物1-5的化学结构。 测试所有化合物的2,2'-唑(3-乙基异噻唑啉-6-磺酸)(ABTS)和1,1-二苯基-2-富铬(DPPH)自由基清除疗效。 化合物1分别表现出显着的抗氧化活性,分别具有31.2和65.4μm的IC 50值和DPPH激进的清除活性。

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    Chonbuk Natl Univ Coll Environm &

    Bioresource Sci Div Biotechnol Iksan South Korea;

    Chonbuk Natl Univ Coll Environm &

    Bioresource Sci Div Biotechnol Iksan South Korea;

    Chonbuk Natl Univ Coll Environm &

    Bioresource Sci Div Biotechnol Iksan South Korea;

    Chonbuk Natl Univ Coll Environm &

    Bioresource Sci Div Biotechnol Iksan South Korea;

    Chonbuk Natl Univ Coll Environm &

    Bioresource Sci Div Biotechnol Iksan South Korea;

    Chonbuk Natl Univ Coll Environm &

    Bioresource Sci Div Biotechnol Iksan South Korea;

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  • 正文语种 eng
  • 中图分类 药学;
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