A new antioxidant, clitocybin A, from the culture broth of Clitocybe aurantiaca.

Kim YH; Cho SM; Hyun JW; Ryoo IJ; Choo SJ; Lee S; Seok SJ; Hwang JS; Sohn ED; Yun BS; Bae KH; Yoo ID

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A new antioxidant, clitocybin A, from the culture broth of Clitocybe aurantiaca.

机译：来自Clitocybe Aurantiaca的培养肉汤的新的抗氧化剂，裂解剂。

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Clitocybin A (1), a new antioxidant, was isolated from the culture broth of Clitocybe aurantiaca. This compound was purified by solvent extraction, silica gel column chromatography, Sephadex LH-20 column chromatography and preparative HPLC. Its structure was determined as 4,6-dihydroxy-2-p-hydroxyphenyl-isoindol1-one on the basis of the UV, NMR, and MS spectroscopic analysis. The compound 1 showed potent free radical scavenging activity against superoxide, ABTS, and DPPH radicals, and protective effect against cellular DNA damage induced by oxidative stress.

机译：克拉氏蛋白A（1）是一种新的抗氧化剂，从Clitocybe Aurantiaca的培养肉汤中分离出来。通过溶剂萃取，硅胶柱色谱，Sephadex LH-20柱色谱和制备型HPLC纯化该化合物。其结构基于UV，NMR和MS光谱分析确定为4,6-二羟基-2-羟基苯基-SOOIndol1-one。化合物1显示出强烈的自由基清除活性对超氧化物，ABTS和DPPH激进的活性，以及针对氧化应激诱导的细胞DNA损伤的保护作用。

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《The Journal of Antibiotics: An International Journal》 |2008年第9期|共4页
作者
Kim YH; Cho SM; Hyun JW; Ryoo IJ; Choo SJ; Lee S; Seok SJ; Hwang JS; Sohn ED; Yun BS; Bae KH; Yoo ID;
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Functional Metabolomics Research Center Korea Research Institute of Bioscience and Biotechnology;

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正文语种 eng
中图分类药学;
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1. A new antioxidant, clitocybin A, from the culture broth of Clitocybe aurantiaca. [J] . Kim YH, Cho SM, Hyun JW, The Journal of Antibiotics: An International Journal . 2008,第9期

机译：一种来自Clitocybe aurantiaca的培养液的新型抗氧化剂ClitocybinA。
2. A new antioxidant, clitocybin A, from the culture broth of Clitocybe aurantiaca. [J] . Kim YH, Cho SM, Hyun JW, The Journal of Antibiotics: An International Journal . 2008,第9期

机译：来自Clitocybe Aurantiaca的培养肉汤的新的抗氧化剂，裂解剂。
3. Clitocybin D, a Novel Human Neutrophil Elastase Inhibitor from the Culture Broth of Clitocybe aurantiaca [J] . Kim Young-Hee, In-Ja Ryoo, Soo-Jin Choo, Journal of microbiology and biotechnology . 2009,第10期

机译：Clitocybin D，一种新型的人类嗜中性粒细胞弹性蛋白酶抑制剂，来自Clitocybe aurantiaca的培养液
4. Antidiabetic Activities of Dry Matters of Culture Broth of Cordyceps militaris in Submerged Culture [C] . Zhang Zuo-fa, Lv Guo-ying, Pan Hui-juan, 5th International Conference on Bioinformatics and Biomedical Engineering . 2011

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7. A New Antioxidant, Clitocybin A, from the Culture Broth of Clitocybe aurantiaca [O] . Young-Hee Kim, Sung-Min Cho, Jin-Won Hyun, 2008

机译：一种新的抗氧化剂，Clitocybin a，来自Clitocybe Aurantiaca的培养肉汤
8. Bone Marrow Aspirate Culture Superior to Streptokinase Clot Culture and 8 ML 1:10 Blood-to-Broth Ratio Blood Culture for Diagnosis of Typhoid Fever [R] . Hoffman, S. L., Edman, D. C., Punjabi, N. H., 1986

机译：骨髓吸出培养优于链激酶凝块培养和8 mL 1:10血液与血液比率血培养诊断伤寒

A new antioxidant, clitocybin A, from the culture broth of Clitocybe aurantiaca.

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