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Anxiety and depressive symptoms among patients infected with human immunodeficiency virus in South Korea

机译:韩国感染人类免疫缺陷病毒的患者的焦虑和抑郁症状

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Patients infected with human immunodeficiency virus (HIV) may develop mental health problems such as anxiety and depression, which negatively impact of disease progression. We investigated factors associated with the prevalence of anxiety and depression symptoms among HIV-infected patients in Korea. A total of 840 HIV-infected patients who participated in the Korea HIV/AIDS Cohort Study from 2006 to 2012 were evaluated. Socio-demographic, epidemiologic, and clinical variables were obtained through standardized questionnaires. The State-Trait Anxiety Inventory and Beck Depression Inventory were used to assess the symptoms of anxiety and depression. Multiple logistic regression analyses were performed to identify factors associated with symptoms of anxiety and depression. The prevalence of anxiety and depressive symptoms among HIV-infected patients was 32% and 36%, respectively. Ex-smoker and persistent symptoms for more than one week within the past six months and diagnosis of HIV infection within one year were associated with increased anxiety symptoms (odds ratio [OR] 1.71, 95% confidence interval [CI] 1.09-2.69; OR 1.52, 95% CI 1.09-2.11; OR 1.49, 95% CI 1.02-2.20) and current smoking and persistent symptoms were also associated with increased depressive symptoms (OR 2.10, 95% CI 1.31-3.30; OR 1.87, 95% CI 1.25-2.79). Marital status, current smoking, current drinking, and persistent symptoms were associated with both increased anxiety and depressive symptoms (OR 1.75, 95% CI 1.07-2.88; OR 1.66, 95% CI 1.06-2.61; OR 1.88, 95% CI 1.18-2.99). The prevalence of anxiety and depressive symptoms among HIV-infected patients is higher than those estimated for the general population. This study shows the necessity to evaluate symptoms of anxiety and depression and suggest psychological support for HIV-infected patients who smoke or have persistent symptoms or have sexual partner or drink.
机译:感染人类免疫缺陷病毒(HIV)的患者可能会出现精神健康问题,例如焦虑和抑郁,这会对疾病的发展产生负面影响。我们调查了在韩国感染HIV的患者中与焦虑和抑郁症状患病率相关的因素。评估了2006年至2012年参与韩国HIV / AIDS队列研究的840名HIV感染患者。社会人口统计学,流行病学和临床变量通过标准化问卷获得。使用状态特质焦虑量表和贝克抑郁量表评估焦虑和抑郁症状。进行了多个逻辑回归分析,以确定与焦虑和抑郁症状相关的因素。 HIV感染患者中焦虑和抑郁症状的患病率分别为32%和36%。在过去六个月内,吸烟者和持续症状持续超过一周,一年内诊断出HIV感染与焦虑症状增加相关(赔率[OR] 1.71,95%置信区间[CI] 1.09-2.69;或1.52,95%CI 1.09-2.11; OR 1.49,95%CI 1.02-2.20)和当前吸烟和持续症状也与抑郁症状增加相关(OR 2.10,95%CI 1.31-3.30; OR 1.87,95%CI 1.25 -2.79)。婚姻状况,当前吸烟,当前饮酒和持续症状与焦虑和抑郁症状增加相关(OR 1.75,95%CI 1.07-2.88; OR 1.66,95%CI 1.06-2.61; OR 1.88,95%CI 1.18- 2.99)。在艾滋病毒感染患者中,焦虑和抑郁症状的患病率高于一般人群的估计值。这项研究表明评估焦虑和抑郁症状的必要性,并为吸烟,持续症状或性伴侣或饮酒的HIV感染患者提供心理支持。

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