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Endoscopic antireflux treatment: fact, fiction or future?

机译:内窥镜反射症治疗:事实,小说或未来?

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摘要

Medical therapy with proton pump inhibitors (PPIs), aside from surgery, is the established and most effective treatment approach for chronic gastroesophageal reflux disease (GERD). Recently developed endoscopic antireflux procedures may be an alternative for a subset of patients with uncomplicated, mild GERD. Given the perioperative morbidity and mortality risk of laparoscopic fundoplication, less invasive semi-surgical and flexible endoscopic techniques may be an option for patients who cannot or wish not to take long-term medication. These clinical procedures include endoscopic suturing devices, focal radiofrequency coagulation in the cardia and bioimplants. While many of these techniques have shown good results in preliminary studies, long-term results are not yet available and therefore all such procedures have to be considered experimental. Their effectiveness will need to be compared with that of established treatment forms.
机译:除手术外,具有质子泵抑制剂(PPI)的医疗疗法是慢性胃食管反流疾病(GERD)的已建立和最有效的治疗方法。 最近,开发的内窥镜反射程序程序可能是一种患者简单,轻度GERD患者的替代品。 鉴于腹腔镜技术的围手术化发病率和死亡率风险,较少的侵袭性半手术和柔性内窥镜技术可能是不能或希望不服用长期药物的患者的选择。 这些临床程序包括内镜缝合装置,贲门和生物蛋白质中的焦射出射凝。 虽然这些技术中的许多技术在初步研究中表现出良好的结果,但尚未提供的长期结果,因此必须考虑所有此类手术。 他们的有效性需要与既定治疗表格的效果进行比较。

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