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首页> 外文期刊>Journal of clinical laboratory analysis. >Evaluation of the UR UR i SCAN SCAN 2 ACR ACR Strip to estimate the urine albumin/creatinine ratios
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Evaluation of the UR UR i SCAN SCAN 2 ACR ACR Strip to estimate the urine albumin/creatinine ratios

机译：评估你的UR我扫描2克拉到ACR ACR TLAD来估计尿液白蛋白/肌酐比率

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Background The urine albumin/creatinine ratio ( ACR ) test is used to screen patients with chronic diseases, such as diabetes, hypertension and cardiovascular diseases that put them at an increased risk of developing kidney disease. Here, we evaluated the performance of the UR i SCAN 2 ACR Strip ( UR i SCAN ; YD diagnostics, Yongin, Korea), a semiquantitative point‐of‐care testing ( POCT ) assay, and we compared to an existing POCT assay and a quantitative assay. Materials and Methods A total of 1,020 random urine specimens were analyzed using the semiquantitative UR i SCAN 2 ACR Strip and semiquantitative CLINITEK Microalbumin 2 Strip ( CLINITEK ; Siemens, New York, USA ). We evaluated the precision of the UR i SCAN 2 ACR Strip and compared the results of the ACR obtained from UR i SCAN to those of CLINITEK with the quantitative results of a quantitative assay as a reference. Results The precision evaluation of the UR i SCAN revealed a range between the cutoff (C 50 )?20% and C 50 +20% bounds, the C 5 ‐C 95 interval, with 85.8% confidence. UR i SCAN and CLINITEK showed sensitivity and specificity of 87.7% and 72.2%, and 90.2% and 83.0%, respectively. The concordance rates of UR i SCAN with CLINITEK and the quantitative assay were 75.6% and 79.1%, respectively. The concordance rate in the abnormal range (≥30?mg/g) between UR i SCAN and the quantitative assay were higher than that between CLINITEK and the quantitative assay (78.8% vs 75.4%). Conclusions UR i SCAN showed good precision and comparable sensitivity with lower specificity than those of CLINITEK .
机译：背景技术尿白蛋白/肌酐比（ACR）试验用于筛选慢性疾病的患者，例如糖尿病，高血压和心血管疾病，使它们增加肾脏疾病的风险。在这里，我们评估了UR I Scan 2 ACR条（UR I Scan; YD Diagnostics，Yongin，Korea）的性能，是一种新的护理点测试（POCT）测定，我们与现有的POCT测定和A相比定量测定。材料和方法使用Scaliquirative UR Scan 2 ACR条和Sequiquiquatiation Clinitek MicroalaMin 2条带（Clinitek; Siemens，纽约，美国），共分析了1,020种随机尿标本。我们评估了UR I Scan 2 ACR条的精度，并将从UR I扫描到Clinitek的ACR的结果与定量测定作为参考的定量结果进行了比较。结果UR I扫描的精确评估显示了截止（C 50）？20％和C 50 + 20％界限的范围，C 5 -C 95间隔，置信85.8％。 UR I Scan和Clinitek显示敏感性和特异性87.7％和72.2％，分别为90.2％和83.0％。 UR I扫描的一致性速率分别扫描和定量测定分别为75.6％和79.1％。 UR I扫描和定量测定之间的异常范围（≥30≤m）的一致性速率高于临床和定量测定（78.8％vs 75.4％）。结论UR我扫描表现出良好的精度和相当的敏感性，比Clinitek的特异性较低。

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