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Validation Prognostic of the Baylor Profound Mental Status Examination

机译：验证八卦深刻精神状态检查的预后

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Background: There are no validated prognostic instruments to evaluate severe Alzheimer's disease (AD) patients. Objective: To validate the prognostic value of the Baylor Profound Mental Status Examination (BPMSE). Methods: We selected 200 patients with severe AD. The following prognostic variables were collected: hospitalization, use of the emergency room, death, and prescription of drugs. ROC curve analysis was performed to see the overall behavior of the test when predicting the adverse event. We analyzed the AUC ROC and the best cut point was determined, and by using contingency tables, the risk was calculated. Results: For a BPMSE >= 16 points, there was a risk of 1.8 (95% CI 0.9-3.4) of prescription of psychotropic drugs in 12 months. For memantine in 12 months, for a BPMSE >= 16 points, there was a risk of 2.9 (95% CI 1.1-7.2). Emergency room visits, for a BMPSE <= 15 points, showed a risk of 1.7 (95% CI 1-3.2). The risk of hospitalization at 12 months, for a BPMSE <= 15, was 1.4 (95% CI 0.8-2.6). When comparing medians, patients with a higher BPMSE were prescribed more drugs at 12 months. Conclusions: BPMSE has a limited predictive value for the variables studied.
机译：背景：没有经过验证的预后仪器来评估严重的阿尔茨海默病（AD）患者。目的：验证八卦深刻精神状态考试的预后价值（BPMSE）。方法：我们选择了200名严重广告的患者。收集以下预后变量：住院，急诊室，死亡和药物的处方。进行ROC曲线分析，以便在预测不良事件时看到测试的整体行为。我们分析了AUC ROC，并确定了最佳切割点，并通过使用应急表，计算风险。结果：对于BPMSE> = 16分，12个月内有1.8（95％CI 0.9-3.4）的危险。对于12个月的Memantine，对于BPMSE> = 16分，风险为2.9（95％CI 1.1-7.2）。急诊室访问，用于BMPSE <= 15分，显示出1.7（95％CI 1-3.2）的风险。为BPMSE <= 15，12个月的住院风险为1.4（95％CI 0.8-2.6）。在比较中位数时，BPMSE患者在12个月内被规定了更多的药物。结论：BPMSE对所研究的变量具有有限的预测值。

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