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首页> 外文期刊>Journal of trace elements in medicine and biology: Organ of the Society for Minerals and Trace Elements (GMS) >The effects of various levels of boron supplementation on live weight, plasma lipid peroxidation, several biochemical and tissue antioxidant parameters of male mice** Effects of boron on performance, antioxidant and some metabolits of mice
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The effects of various levels of boron supplementation on live weight, plasma lipid peroxidation, several biochemical and tissue antioxidant parameters of male mice** Effects of boron on performance, antioxidant and some metabolits of mice

机译：各种水平硼补充对活重，血浆脂质过氧化，几种生物化学和组织抗氧化参数的影响，硼对小鼠性能，抗氧化和一些代谢的影响

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摘要

In this study, live weight, live weight gain, plasma GPx, GR, LDH, ALT activities, triglyceride, total protein, albumin and LPO levels, also liver and brain SOD and GPx activities were investigated after administration of boron (0.10, 0.20 and 0.30 mg/day) into male mice with drinking water for 60 days. Blood albumin and triglyceride levels were not affected with boron (p 0.05) where triglyceride levels, with increasing amounts of boron, displayed a slight decrease within the normal ranges. From the antioxidant-oxidant balance parameters, LPO and GR levels were not affected from boron, where GPx activity was increased significantly (p 0.001) comparing the groups of boron and control. LDH and ALT activities were affected significantly (p 0.001) with decreased ALT and increased LDH levels with increasing amounts of boron. In regards of liver and brain GPx and SOD activities, significant increases were determined. Liver GPx and SOD activities were increased within the groups with the increasing amount of boron, where in brain, SOD (p 0.05) was affected significantly but GPx (p 0.05) displayed a gradual insignificant increase. As regards live weight gain, a gradual increase was determined during experimental period, but only the 45th day, the increase was statistically significant (p 0.05). It is suggested that, new studies on the effects of different doses and compounds of boron in laboratory animals in regards of antioxidant and metabolic effects may be helpful for the understanding of the subject.
机译：在本研究中，在施用硼（0.10,0.20和0.30毫克/天）进入雄性小鼠，饮用水60天。硼（P＆GT; 0.05）的硼（P＆GT; 0.05）没有影响血液白蛋白和甘油三酯水平，其中甘油三酯水平随着量增加的硼，在正常范围内显示出轻微的减少。从抗氧化剂 - 氧化剂平衡参数，LPO和GR水平不受硼的影响，其中GPX活性显着增加（P <0.001）比较硼和对照组。 LDH和ALT活性显着影响（P <0.001），随着ALT的降低和增加的LDH水平随着量增加的硼。关于肝脏和脑GPX和SOD活性，确定显着增加。肝脏GPX和SOD活性在群体中增加了含量越来越多的硼，其中SOD（P <0.05）显着影响，但GPX（P＆GT; 0.05）显示出逐渐微不足道。至于实时体重增加，在实验期间确定逐渐增加，但只有第45天，增加统计学意义（P <0.05）。建议，关于抗氧化剂和代谢效应在实验动物中不同剂量和硼化合物在实验室动物中的影响的新研究可能有助于了解对象的理解。

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