Bacterial Lectin-Targeting Glycoconjugates for Selective Elimination of Pathogenic Bacteria

Ji Young  Hyun; Chang-Hee  Lee; Hosoowi  Lee; Woo-Dong  Jang; Injae  Shin

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Bacterial Lectin-Targeting Glycoconjugates for Selective Elimination of Pathogenic Bacteria

机译：细菌凝集素靶向糖缀合物，用于选择性消除致病细菌

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Herein we report a strategy to eradicate pathogenic bacteria selectively, which utilizes bacterial lectin-targeting glycoconjugates that contain an epitope or a photosensitizer to promote antibody-dependent cellular cytotoxicity (ADCC) or photodynamic therapy (PDT), respectively. Our results show that death promoted by using the designed synthetic glycoconjugates coupled with ADCC or PDT takes place selectively in pathogenic bacteria expressing lectins on their surfaces.

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《ACS Macro Letters》 |2020年第10期|共4页
作者
Ji Young Hyun; Chang-Hee Lee; Hosoowi Lee; Woo-Dong Jang; Injae Shin;
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Department of Chemistry Yonsei University;

Department of Chemistry Yonsei University;

Department of Chemistry Yonsei University;

Department of Chemistry Yonsei University;

Department of Chemistry Yonsei University;

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原文格式 PDF
正文语种 eng
中图分类有机化学;
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10. Bacterial Lectin-Targeting Glycoconjugates for Selective Elimination of Pathogenic Bacteria [O] . -1

机译：用于选择性消除致病性细菌的细菌凝集素靶向糖凝集蛋白
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Bacterial Lectin-Targeting Glycoconjugates for Selective Elimination of Pathogenic Bacteria

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