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首页> 外文期刊>Antimicrobial agents and chemotherapy. >Killing of Neisseria gonorrhoeae, Streptococcus agalactiae (group B streptococcus), Haemophilus ducreyi, and vaginal Lactobacillus by 3-O-octyl-sn-glycerol.
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Killing of Neisseria gonorrhoeae, Streptococcus agalactiae (group B streptococcus), Haemophilus ducreyi, and vaginal Lactobacillus by 3-O-octyl-sn-glycerol.

机译:用3-O-辛基-sn-甘油杀死淋病奈瑟氏球菌,无乳链球菌(B组链球菌),杜克雷嗜血杆菌和阴道乳杆菌。

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摘要

The microbicide candidate octylglycerol inactivates sexually transmitted bacterial pathogens at concentrations which spare normal vaginal flora (lactobacillus). Standard minimum microbicidal concentration assays and time-kill assays revealed the drug concentrations and times required for inactivation. Octylglycerol concentrations must exceed the binding capacity of any human serum albumin to be effective.
机译:候选杀微生物剂辛基甘油可以使正常阴道菌群(乳杆菌)免除的浓度使性传播的细菌病原体失活。标准的最小杀微生物浓度测定法和时间杀灭测定法揭示了灭活所需的药物浓度和时间。辛基甘油浓度必须超过任何人血清白蛋白的结合能力才能有效。

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